There is no effective therapy for HCM and generally for cardiac hypertrophy.
HCM和心肌肥厚缺乏有效的治疗方法。
Objective To study the effect of CARK, a cardiac specific kinase, on cardiac hypertrophy.
目的:探讨心肌细胞特异表达的基因CARK在心肌细胞中的作用。
ECG abnormalities with ST-T change the common, followed by arrhythmia, such as cardiac hypertrophy.
心电图异常以ST - T改变为常见,其次分别为心律失常、心肌肥厚等。
AIM To investigate the relationship between myocardium chymase like activity and cardiac hypertrophy.
目的探讨心肌肥厚与心肌组织糜酶样活性的关系。
Objective To evaluate the effect of perindopril on ventricular tachycardia in rabbits with cardiac hypertrophy.
目的观察培垛普利对兔肥厚心肌室性心律失常的保护作用。
AIM: To investigate the role of phosphoinositide pathway in the formation of pressure-overload cardiac hypertrophy.
目的:探讨肌醇磷脂途径在压力超负荷性心肌肥厚形成中的作用。
It suggested that the ability of anti-injury in exercise-induced cardiac hypertrophy is higher than that in hypertension.
本研究提示运动性心肌肥大的心肌抗缺血再灌注损伤的能力较高血压心肌肥大者增强。
Here we reviewed the progress of researches on the mechanism of cardiac hypertrophy and discussed its putative mechanisms.
本文综述了近年来心肌肥厚发生机制的若干研究进展,同时探讨了心肌肥厚发生的可能机制。
Objective:To investigate the changes of plasma biological active peptides in exercise-induced cardiac hypertrophy in rats.
目的:研究运动性心肌肥大形成中血浆生物活性肽的含量及意义。
AIM: To study the effect of insulin on proliferation and hypertrophy of cardiac myocytes and its role in the induction of cardiac hypertrophy.
目的:研究胰岛素对心脏细胞增殖和心肌细胞肥大的影响,探讨其在心肌肥厚中的作用。
The balance between ADM and ET was destroyed and it was probably one of the critical reasons in the pathological process of cardiac hypertrophy.
ADM间的动态平衡被打破可能是心肌肥厚发病的重要原因之一。
In this process, cardiac hypertrophy is characterized by an increase in cell size and protein synthesis and reactivation of the fetal gene program.
在这个过程中常常伴有心肌细胞体积增大、心肌纤维增生和胚胎基因的重新激活。
These results proved that polycythemia may play an important role in pathogenesis of chronic hypoxic pulmonary hypertension and cardiac hypertrophy.
以上结果表明红细胞增多可能在慢性缺氧性肺动脉高压和右室肥大发生起着重要作用。
Objective: To investigate the regressive effect of total glucosides of Paeonia Lactiflora (TGP) on cardiac hypertrophy induced by L-thyroxine(L-Thy) in rats.
目的:考察芍药总甙对L-甲状腺素所致大鼠心肌肥厚的消退作用。
The main interest of the laboratory is focused on the signal transduction pathway during cardiac hypertrophy and the effect of adiponectin on cardiac function.
本研究室的主要研究方向为心肌肥大时的细胞信号转导通路及脂联素对心脏功能的影响。
Conclusion QTd was decreased in exercise-induced cardiac hypertrophy subjects, which may reflect homogeneous myocardial repolarization in long term trained subjects.
结论运动诱导的心肌肥厚使QT离散度减小,反映了长期运动个体心肌复极化的稳定性。
At present , the recognization is agreed on that cardiac hypertrophy belongs to regulatory and physical cardiac enlargement. But its mechanisms are still not be stated clearly.
目前,对运动性心肌肥大属于调节性、生理性肥大的认识渐趋一致,但其发生机制尚未完全阐明。
Reactive oxygen species can mediate signalling pathways in cardiac hypertrophy and cardiomyocyte apoptosis, and lead to endothelial dysfunction by inactivating nitrogen monoxide.
活性氧通过信号通路介导心肌细胞肥大和凋亡;通过灭活一氧化氮等机制导致内皮功能紊乱。
In this article we only reviewed the biological mechanism of exercise induced cardiac hypertrophy by its inductive stimulus, pass way for signal transduction and genetic expression.
仅从运动性心肌肥大的生物学机制方面,就诱导其发生的刺激因素及其信号转导通路、基因表达等几个方面加以综述。
CONCLUSION: CsA can inhibit hypertensive cardiac hypertrophy, but large dose or longer period of application will lead to severe myocardial edema, which is dose-dependent and time-dependent.
结论:环孢霉素A可抑制高血压心肌肥大,但较大剂量或较长时间应用则会产生严重心肌水肿,并且这种作用是剂量、时间依赖性的。
Conclusion: Zhimu combined with Huangqi can slow down heart rate, enhance the reserve force of the heart, and improve the response capacity of cardiac hypertrophy mice in stimulative condition.
结论:知母、黄芪合用能减慢心率,提高心肌储备,改善实验性心肌肥厚小鼠对应激反应的能力。
Background and Objective: Cardiac hypertrophy serves as a common pathway in various cardiovascular diseases. It is one of the most important pathological foundations resulting in cardiogenic death.
背景与目的:心肌肥大是多种心血管疾病的共同病理过程,是导致心原性死亡的最重要的病理基础之一。
OBJECTIVE: to study the value of Xstrain technology in the evaluation of cardiac function in children with tonsil adenoidal hypertrophy.
目的:探讨心肌矢量应变技术在检测扁桃体腺样体肥大患儿心脏功能方面的应用价值。
The cardiac muscle cell hypertrophy is a complicated dynamic process with many regulation factors to participate in.
心肌细胞肥大是一种多因素参与调节的复杂的动态过程。
Objective To evaluate the effects of Conbination valsartan with Captopril on Cardiac function and left ventricular hypertrophy(LVH) in hypertensive patients.
目的探讨缬沙坦联用卡托普利与单用卡托普利比较,对高血压患者心功能及左心室肥厚的影响。
Results: Research indicated that Leptin and Leptin receptor (OB-Rb) was closely related to the pathogenesis of Hypertensive Cardiac Myocyte Hypertrophy.
结果:研究表明瘦素和瘦素受体与高血压心肌肥厚的发病机制有密切关系。
The characteristics of hypertrophic cardiomyopathy (HCM) are hypertrophy of ventricular muscle and increase of cardiac weight.
肥厚型心肌病(HCM)病变特征为心室肌肥厚,心脏重量增加。
DATA SYNTHESIS: During continuous exercise, myocardium hypertrophy induced by exercise was the physical basis of the increase in cardiac output.
资料综合:在持续性运动期间运动诱导心肌肥大是心输出量增加的生理基础。
In this text, we reviewed the effect of atorvastatin on the treatment of cardiac myocyte hypertrophy.
本文从心肌细胞肥大这个角度阐述阿托伐他汀对心室重塑的影响。
Conclusion Simvastatin can inhibit the hypertrophy of cultured rat cardiac myocytes induced by serum, the mechanism of which might be related with the increase of PTEN expression.
结论辛伐他汀能够抑制血清诱导的心肌细胞肥大,升高pten表达水平可能是其分子生物学机制之一。
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