Eberhart and colleagues studied glioblastoma cell lines to investigate the effects of a gamma-secretase inhibitor, a medication that blocks the Notch receptor, on tumor growth.
埃伯哈特和他的同事们研究了恶性胶质瘤的细胞系以发现γ-内分泌酶抑制剂的影响,这种药物可阻断促使肿瘤增长的Notch受体途径。
Objective To evaluate the inhibiting effect of selective and non-selective cyclo-oxygenase-2(COX-2) inhibitor on growth of colon cancer cell lines in vitro and its signal transduction pathway.
目的探讨选择性及非选择性环氧合酶-2抑制剂(COX-2)对体外培养的结肠癌细胞生长的影响及其作用的信号传导通路。
Conclusion: Epidermal growth factor receptor inhibitor AG1487 may retard cell cycle, and then inhibit the proliferation of tumor cells.
结论:表皮生长因子受体抑制剂ag1487可对舌鳞癌细胞产生明显的增殖抑制作用。
ObjectiveTo investigate the antitumor effect of MS275, a histone deacetylase inhibitor, on growth of the human myeloma cell line U266.
目的研究组蛋白去乙酰化酶抑制剂MS275对人多发性骨髓瘤细胞U266增殖的影响。
Brefeldin a is a potent inhibitor of cell growth first described in 1958, then independently "rediscovered" by several groups as a potent active in a broad range of bioassays.
布雷非德菌素是一种高效的细胞生长抑制剂。1958年第一次被报导,之后又被几个研究小组在一系列不同的生物化验中作为高效活性试剂。
Objective: to investigate the influence of TOFA, a Acetyl CoA Carboxylase inhibitor, on cell growth of human ovarian cancer cell line COC1, and explore the mechanism.
目的:探讨乙酰辅酶A羧化酶抑制剂TOFA对卵巢癌COC1细胞增殖能力的抑制作用及其机制。
Telomerase activity were detected by TRAPELISA. Results: Telomerase antisense oligodeoxynucleotides acted as a specific growth inhibitor to gastric cancer cell line.
结果:端粒酶反义寡聚脱氧核苷酸能诱导人胃癌细胞凋亡,抑制端粒酶活性。
Telomerase activity were detected by TRAPELISA. Results: Telomerase antisense oligodeoxynucleotides acted as a specific growth inhibitor to gastric cancer cell line.
结果:端粒酶反义寡聚脱氧核苷酸能诱导人胃癌细胞凋亡,抑制端粒酶活性。
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