Telomere and telomerase play important roles in the process of cellular senescence.
端粒及端粒酶在细胞的衰老过程中扮演着重要角色。
But cancer cells appear to remain forever young: how do they escape cellular senescence?
但是癌细胞似乎可以保持永远年轻：它们是怎样逃脱细胞老化的呢？
We postulate that SPATA4 gene is very likely to be involved in the process of cellular senescence and aging.
我们推测SPATA4基因极有可能参与到细胞衰老乃至个体衰老的过程中。
Cellular senescence may contribute to the ageing of organisms, and is closely related to tumor suppression.
细胞老化可能促进生物衰老，并且与肿瘤发生受抑密切相关。
Cellular senescence has been recently shown to have an important role in opposing tumour initiation and promotion.
细胞衰老已经在抑制肿瘤产生和扩展中显示出了重要的作用。
This was the first link between the molecular biology of telomeres and cellular senescence, the aging and death of cells.
这是端粒的细胞生物学首次与细胞的衰老及死亡联系在一起。
It hinted at the importance of cellular senescence, but wasn't so convincing as if the mice had senesced over the course of their lives, then been treated.
该实验暗指细胞老化的重要性，但说服力不够，因为如果实验鼠在衰老过程中得到治疗，又会发生什么结果。
This research reveals that SPATA4 gene can inhibit cellular senescence and apoptosis as well as promote the progression of cell cycle and cell proliferation;
本研究发现SPATA4基因能够抑制细胞衰老和细胞凋亡、促进细胞周期的推进与细胞增殖；
Conversely, if telomerase activity is high, telomere length is maintained, and cellular senescence is delayed. This is the case in cancer cells, which can be considered to have eternal life.
相反，如果端粒酶一直保持较高的活力，则端粒的长度就能保持下去，而细胞衰老的进程就会被推迟，这种情形可见于癌细胞：一类属于永生的细胞。
Conversely, if telomerase activity is high, telomere length is maintained, and cellular senescence is delayed. This is the case in cancer cells, which can be considered to have eternal life.
相反，如果端粒酶一直保持较高的活力，则端粒的长度就能保持下去，而细胞衰老的进程就会被推迟，这种情形可见于癌细胞：一类属于永生的细胞。
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