Objective To analyze the chromosomal changes and its clinical significance in childhood acute lymphoblastic leukemia (ALL).

目的研究儿童急性淋巴细胞白血病(all)染色体变化，探讨其临床意义。

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Objective To analyse the treatment outcome of 158 childhood acute lymphoblastic leukemia (ALL) patients, and explore how to improve the event-free survival(EFS) rate in ALL.

目的对15 8例儿童急性淋巴细胞白血病（ALL）患儿治疗结果进行分析，探讨如何进一步提高儿童ALL无事件生存（EFS）率。

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Objective: to analyse the treatment outcome of childhood acute lymphoblastic leukemia (ALL) patients in our hospital, and explore the factors influencing the Disease-free survival (DFS).

目的：总结湘雅医院近年住院治疗儿童急性淋巴细胞性白血病(all)临床资料，探讨影响儿童all长期无病生存(DFS)的因素。

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Objective:To analyse the adverse drug reaction of high dose methotrexate (HD-MTX) in treatment of childhood acute lymphoblastic extramedullary leukemia (ALL).

目的：剖析比拟出口与国产甲氨蝶呤（HD-MTX）在预防治疗儿童急性淋巴细胞髓外白血病进程中不良反响的发作率。

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Objective:To analyse the adverse drug reaction of high dose methotrexate (HD-MTX) in treatment of childhood acute lymphoblastic extramedullary leukemia (ALL).

目的：剖析比拟出口与国产甲氨蝶呤（HD-MTX）在预防治疗儿童急性淋巴细胞髓外白血病进程中不良反响的发作率。

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