The effects of composition of mobile phase, the structure of solute and the column temperature on chiral separation were extensively studied. The chiral recognition mechanism was discussed.
考察了流动相组成、溶质结构和柱温对对映体分离的影响,并初步探讨了手性识别的机理。
A test is carried out after homogenate is filled into the chromatogram column, thus successfully separating chiral medicine ibuprofen enantiomers with a separation degree of 2.03.
匀浆填充成色谱柱后对其进行了测试,成功分离了手性药物布洛芬对映体,其分离度为2.03。
A cinchonine imprinted chiral monolithic column was prepared for the separation of the diastereomers of cinchonine and cinchonidine by in situ molecular imprinting technique.
采用原位分子印迹技术,单步制备了一种辛可宁印迹的手性整体柱。
The thermodynamic and kinetic in the chiral separation process on the molecularly imprinted monolithic column were studied.
研究了分子印迹整体柱手性拆分过程的热力学和动力学。
The CDMPC CSP was synthesized and the chiral column was prepared which showed favorable enantiomeric recognition and separation potency.
合成了CDMPC手性固定相并制得手性柱,对手性农药乙氧呋草黄和稻丰散对映体具有很好的识别和拆分能力。
OBJECTIVE: to establish a pre column chiral derivatization reversed phase high performance liquid chromatographic method for the separation of ketoprofen enantiomers.
目的:建立柱前手性衍生化反相高效液相色谱法分离酮洛芬对映体的方法。
OBJECTIVE: to establish a pre column chiral derivatization reversed phase high performance liquid chromatographic method for the separation of ketoprofen enantiomers.
目的:建立柱前手性衍生化反相高效液相色谱法分离酮洛芬对映体的方法。
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