Unlike nitroglycerine, it is not rapidly inactivated in the liver and a reliable clinical effect can be expected. Toxicity is low-effects are minimal with Motazomin.
脉心导敏与硝酸甘油不同，在肝脏不能迅速失活，因而可望具有可靠的临床效果，本品毒性小，副作用极为轻微。
It goes fine for a while, but Phase III of clinical trials uncovers some unexpected toxicity.
现阶段还好，但是一到临床试验的第三个阶段，药物就会出现很多无法预期的毒性。
The toxicity of balaglitazone was characterized in a comprehensive non-clinical toxicology programme.
巴格列酮的毒性已经经过一个综合性的非临床毒理研究程序鉴定。
Although there was much preclinical interest in the antibiotic geldanamycin as an anti-cancer drug, it turned out to be a poor candidate for clinical trials because of its toxicity.
尽管在临床前试验中抗生素格尔德霉素表现出很强的作为抗癌药物的潜力，但是因为其毒性，这种药物没有能成为具有良好临床试验前景的候选药物。
Objective to evaluate the clinical efficacy and toxicity of ifosfamide (ifo) combination chemotherapy in patients with advanced gynecologic malignancies.
目的对异环磷酰胺(ifo)联合化疗治疗晚期妇科恶性肿瘤进行临床疗效和毒性评价。
Objective: to evaluate the clinical effect and toxicity of gemcitabine monotherapy in the treatment of elder advanced non-small cell lung cancer (NSCLC).
目的观察了解吉西他滨单药治疗老年晚期非小细胞肺癌(NSCLC)的临床疗效和毒性反应。
ResultsIn the experiment of acute toxicity, the maximum tolerance dosage by gavage in mice was 160 times of the clinical dosage in humans.
结果急性毒性实验小鼠灌胃给药最大耐受量相当于人临床日用量的160倍。
"Although we observed no toxicity in our experiments, clinical translation of this method will require formal toxicity studies," they added.
“虽然在我们的试验中没有观察到毒性，但如果这种方法进行临床应用还需要进行正规的毒性研究，”他们补充说。
ConclusionRujiean capsule is safe to be used in clinical practice and had no acute and chronic toxicity.
结论乳洁安胶囊拟定剂量，途径及疗程在临床应用上是安全的。
This paper introduces mechanism and feature of the toxicity in sensory ganglion of adriamycin as well as clinical application.
本文将重点介绍阿霉素对感觉神经节细胞的毒性机制、特点及其临床应用。
Conclusion Animals have good tolerance to the new drug with low toxicity, which is safe for clinical research.
结论动物对该药物有很大的耐受性，毒性低，可以进一步深入临床研究。
Thallium geochemical properties, distribution, physiological toxicity, clinical symptoms, chemical migration and transformation in the environment were reviewed.
介绍了铊的地球化学性质、分布状况、生理毒性和临床表现及环境迁移转化过程。
Objective to analyze the clinical features of primary central nervous system lymphoma (PCNSL), and to assess the efficacy and toxicity of combined chemotherapy.
目的探讨原发性中枢神经系统淋巴瘤(PCNSL)的临床特点，评估联合化疗的效果及其毒性。
Objective to evaluate efficacy and acute toxicity of rhinitis capsules so as to provide a scientific proof of modern pharmacology and security for clinical work.
目的检测鼻炎胶囊的有效性和急性毒性反应，为临床提供现代药理学及安全用药的科学依据。
Study drugs have been done a series of pharmacology, toxicity and animal testing before clinical trials.
试验用药在开始用于人的临床试验之前会进行一系列的药理学、毒性以及动物试验。
OBJECTIVE: to evaluate the long-term toxicity of Ginkgolide B injection on Beagle dogs, and to provide safety evidences for clinical experiment.
目的：研究银杏内酯B注射液的长期毒性，为临床试验提供安全性依据。
To study the clinical toxicity and attenuation of Leucaena in broilers, 250 10-day-old AA broilers were randomly divided into five groups, which every group had 50 broilers.
为研究银合欢对肉鸡的临床毒性和减毒作用，250只10日龄aa肉鸡随机分为五组，每组50只。
The results suggest that folic acid or folinic acid can protect the less differentiated cells in the intestinal crypts, so that the clinical manifestations of NQD toxicity are reduced after treatment.
提示用叶酸或甲酰四氢叶酸钙后能保护复方硝喹对小肠的破坏，因而会大大减轻其临床毒性反应。
Objective to evaluate the clinical efficacy and toxicity of CEF as the neoadjuvant chemotherapy regimen in the treatment of locally advanced breast cancer (LABC).
目的评价CEF方案新辅助化疗治疗局部晚期乳腺癌的临床疗效和毒性反应。
The producers of the electronic cigarettes have not conducted clinical studies and toxicity analysts, and consequently, the cigarettes are potentially dangerous.
电子卷烟的制造商没有进行临床研究和毒性分析，因此，这种卷烟具有潜在的危险性。
However, it is still unclear whether proton therapy treatments have a clinical advantage in either decreasing toxicity or improving local control and survival.
尽管如此，质子疗法无论是在减低毒性，还是改善局部肿瘤控制或幸存率等临床上的优势还不明确。
So monitoring serum concentration and predicting toxicity of 5-FU mean clinical sense.
因此，5-FU血药浓度监测和毒副反应严重程度的预测具有重要的临床意义。
Objective: to review Tripterygium Wifordii as immunosuppressant in the clinical toxicity and clinical attenuated method.
目的：综述雷公藤作为免疫抑制剂在临床上的毒副反应及临床减毒方法。
The acute toxicity of gefitinib up to 500 mg in clinical studies has been low.
急性毒性吉非替尼多达500毫克的临床研究一直很低。
These are the key technology to the successful conduction of clinical reproductive toxicity test on drugs.
这些都是能够成功开展药物非临床生殖毒性试验的关键技术。
These are the key technology to the successful conduction of clinical reproductive toxicity test on drugs.
这些都是能够成功开展药物非临床生殖毒性试验的关键技术。
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