Objective: To investigate the activities of tumor infiltrating lymphocytes(TILs) stimulated by dendritic cells(DCs) on mouse breast cancer cells in vitro.
目的:探讨致敏的树突状细胞(DC)激活的肿瘤浸润淋巴细胞(TIL)体外抗小鼠乳腺癌活性。
Objective: to elucidate the effect of APS on inducing the cord blood monocyte in vitro into the dendritic cells (DCs).
目的:探讨黄芪多糖在体外对脐血单核细胞向树突状细胞分化的作用。
Objectve: To investigate whether the dendritic cells(DCs) loaded with the peptide derived from MAGE-A3 could induce specific cytotoxic T lymphocytes(CTLs) response in breast cancer patients in vitro.
目的研究MAGE-A3抗原肽负载对乳腺癌患者树突状细胞(DC)的功能的影响,探讨其是否可以在体外诱导特异性细胞毒性T淋巴细胞(CTL)应答。
Objective To observe the expressions of CD1C and S-100 in dendritic cells(DCs) of human breast cancer.
目的观察CD1C和S-100蛋白在人乳腺癌组织中树突状细胞(DC)的表达。
It has been proved that Dendritic cells (DCs) have strongly ability to present antigen. DCs can trigger t cell responses and enhance the t cell mediated anti tumor effect.
树状突细胞(DC)具有强大的抗原递呈能力,并能有效激发T细胞应答,是目前抗肿瘤免疫治疗研究的热点之一。
Objective to investigate the therapeutic effects on pancreatic carcinoma by dendritic cells (DCs) transfected with interleukin (IL) -23 and acquiring apoptotic cell antigen.
目的探讨白细胞介素23 (IL - 23)基因转染的树突状细胞(DC)负载凋亡癌细胞抗原后诱导的免疫应答对小鼠胰腺癌的治疗作用。
Objective to investigate the effects of high mobility group box-1 protein (HMGB1) on surface receptor expression of splenic dendritic cells (DCs) and its potential mechanism in rats.
目的观察高迁移率族蛋白b 1 (HMGB1)对大鼠脾脏树突细胞(DC)作用的受体机制。
Depending upon cell types and microenvironment, CD24 can induce apoptosis and induce immune tolerance in dendritic cells (DCs).
而且随着不同细胞型别和生物学环境的变化,CD 24也起着诱导凋亡或促进树突状细胞的免疫耐受作用。
METHODS: Dendritic cells (DCs), induced from peripheral blood mononuclear cells (PBMCs) by cytokines, were confirmed by morphological observation and FACS.
方法:以细胞因子从外周血单个核细胞(PBMC)中诱导树突状细胞(DC),通过形态学观察和流式细胞术进行鉴定。
Objective To investigate antitumor effects induced by dendritic cells (DCs) pulsed with complex of tumor antigen from elemene-combo tumor cell vaccine-heat shock protein 70 of BCG (HTA-HSP70BCG).
目 的观察体外构建的榄香烯复合瘤苗抗原-卡介苗 热休克蛋白70复合物(HTA-HSP70BCG)诱导 的树突状细胞疫苗 的抗肿瘤效应。
AIM: To isolate, culture and identify in vitro of dendritic cells (DCs) from human peripheral blood, and observe the function of antigen presentation.
目的:体外分离培养并鉴定人外周血树突状细胞,并观察其抗原呈递功能。
Dendritic cells (DCs) have different subtypes with distinct phenotypes and biological functions. Meloyiod dendritic cell subtype is one of the most important DCs subtypes.
树突状细胞由多种表型特征及生物学功能特性不同的亚群组成,单核细胞源性树突状细胞是其中的重要组成群体。
Objective To study the effects of mature dendritic cells (DCs) derived from mouse bone marrow on T cell proliferation in vitro, and provide techinological methods for tumor therapy.
目的:研究小鼠骨髓干细胞体外诱导分化的树突状细胞对T细胞增殖的影响,为进一步研究树突状细胞的功能及临床肿瘤的治疗提供有效的实验方法。
Objective to obtain dendritic cells (DCs) from peripheral blood stem cells and hematopoietic precursor cells in vitro, and assess the feasibility of clinical application of tumor vaccine.
目的探讨由动员人外周造血祖细胞体外培养扩增获得的树突状细胞(DC)的生物学特性,为临床应用肿瘤树突状细胞疫苗建立制备方法。
Methods The dendritic cells(DCs) were cultured in vitro and induced by SPA. The activity of CTLs was detected by MTT.
方法采用急性粒细胞白血病细胞可溶性蛋白抗原致敏体外培养的DC,并通过MTT法测定CTL活性。
Methods Co-culture tumor antigen-sensitized dendritic cells (DCs) with cytokine induced killer (CIK) cells, analyze the immune epitope and determine the killing effect on tumor cells by MTT method.
方法采用肿瘤抗原致敏的DC与CIK细胞共培养,分析其免疫表型,并用mtt染色法检测其对肿瘤细胞的杀伤力。
Methods Co-culture tumor antigen-sensitized dendritic cells (DCs) with cytokine induced killer (CIK) cells, analyze the immune epitope and determine the killing effect on tumor cells by MTT method.
方法采用肿瘤抗原致敏的DC与CIK细胞共培养,分析其免疫表型,并用mtt染色法检测其对肿瘤细胞的杀伤力。
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