Focus on the bioinformatics analysis of DNA methylation.
主要研究dna甲基化的生物信息学分析。
DNA methylation is one of the most common epigenetic events in eukaryotic cell.
DNA甲基化是真核细胞基因组最常见的一种表观遗传学修饰。
DNA methylation plays an important role in gene regulation and animal development.
DNA甲基化在基因调节和动物发育中起着重要作用。
DNA methylation is the unique natural covalent modification of vertebrate animals.
DNA甲基化是脊椎动物DNA唯一的自然共价修饰方式。
"DNA methylation in the kidney is different from DNA methylation in the liver," he says.
“肾脏内的DNA甲基化不同于肝脏内的，”他说。
DNA methylation may be an important mechanism of inactivation of RUNX3 gene in HCC.
甲基化机制可能是肝细胞癌runx3基因失活的重要机制之一。
When a methyl group attaches to a specific spot on a gene - a process called DNA methylation.
甲基附加到基因上某个特殊点的过程，称为DNA甲基化。
It is clear that tight regulation of DNA methylation is necessary for normal development.
很明显，DNA甲基化的严格调控对于正常发育是必需的。
Here, we review the role of epigenetics in aging and longevity with a focus on DNA methylation.
这里，我们回顾了表观遗传学在衰老和长寿中的作用，集中在DNA甲基化。
Recent studies on DNA methylation and its regulatory enzymes, seem hot to researches of epigenetics.
DNA甲基化及其调节酶是近年来表观遗传学研究的热点。
DNA methylation and its aberrance play an important role in the human development and tumorigenesis.
DNA的甲基化及甲基化异常在人体发育和肿瘤的发生中起着至关重要的作用。
DNA methylation in the promoter regions is a powerful mechanism for the suppression of gene activity.
在启动子区域的DNA甲基化是抑制基因活性的一种重要机制。
The work is one of several clues that DNA methylation affects the formation and maintenance of memories.
这项工作是DNA甲基化影响记忆形成和延续的线索之一。
The heterogeneities of the F1 genomes were associated with the readjustments in DNA methylation pattern.
F1代基因组的杂合性与基因组DNA甲基化模式的重新调整有关。
The system of Epigenetics includes DNA methylation, RNA-interfering, genome imprinting and histone code and so on.
表遗传体系包括DNA甲基化、RNA干涉、基因组印迹和组蛋白密码等多方面。
Many studies showed that DNA methylation is specific marker of NSCLC in its diagnosis, staging, treatment and prognosis.
研究显示，DNA甲基化是非小细胞肺癌（NSCLC）诊断、分期及治疗预后特异性较强的标识物。
Researchers looked for - and found - a chemical change called DNA methylation in healthy tissue adjacent to breast tumors.
研究者寻找并发现了靠近肿瘤组织的健康组织中有“DNA甲基化”这种化学改变。
Correlation analysis was processed among serum folate concentration of dam and fetus and DNA methylation level in fetal brain.
期末血清叶酸、胎鼠血清叶酸及胎鼠脑组织DNA甲基化水平作相关分析。
We will discuss methods to address these challenges in the context of analyzing histone modifications and DNA methylation data.
我们将在分析组蛋白修饰和DNA甲基化数据的背景下，讨论解决这些挑战的方法。
When you use animal models and do the things that are commonly done in assisted reproduction, the answer is yes—it affects DNA methylation.
“如果你在动物模型上模拟辅助生殖你会发现答案是肯定--它能影响DNA的甲基化”。
The process, known as DNA methylation, is one mechanism of epigenetic change, heritable change that does not alter the sequence of DNA itself.
该过程被成为DNA甲基化，是表观遗传变化的一种，属于不会改变DNA序列的可遗传变化。
The plants were derived from two Arabidopsis parents with essentially identical genomes, but with one having a mutated DDM1 DNA methylation gene.
这些植株源自两棵基因几乎相同的拟南芥，但其中一棵含有突变的DDM1甲基化DNA。
Frequencies of decrease in DNA methylation sites among cultivars were in this order: V27, V14, and R09, V27 showing more demethylation sites.
DNA甲基化变化频率递减的顺序依次是：V27、V14、R 09； V27品系显现出更多的去甲基化的位点。
Polyamines change structure of chromosome and interfere with DNA methylation process, which is involved in the pathogenesis of autoimmune diseases.
多胺改变了染色体的正常结构，干扰了DNA的甲基化过程，在自身免疫性疾病中的发病作用近来引起了人们的关注。
Andrew Hudson at the University of Edinburgh says there is a clear implication that "DNA methylation and epigenetic changes are important in evolution."
爱丁堡大学的AndrewHudson表示，这明显意味着“DNA甲基化和表观基因变异在进化中是非常重要的”。
Discussing the relations of DNA methylation and gene transcriptional silencing takes on important significances for the study of many human diseases.
探讨DNA甲基化与基因转录抑制之间的关系，对许多人类疾病的研究具有重要意义。
More and more studies during recent years discovered that abnormal DNA methylation is closely correlative with neoplasms, autoimmune diseases and senility.
近年来，越来越多的研究发现异常的DNA甲基化和肿瘤、自身免疫性疾病、衰老等密切相关。
This article briefly discusses plant DNA methyltransferase, the mode and the loci of methylation and the epigenetic phenomenon originated by DNA methylation.
简要论述了植物dna甲基转移酶、甲基化方式、发生位置及DNA甲基化所引起的表观遗传现象。
The state of DNA methylation is reversible, therefore utilization of DNA methylation inhibitors may offer an expectation for prevention and treatment of tumor.
由于DNA甲基化状态是可以改变的，故利用DNA甲基化抑制剂达到防治肿瘤的目的成为可能。
The state of DNA methylation is reversible, therefore utilization of DNA methylation inhibitors may offer an expectation for prevention and treatment of tumor.
由于DNA甲基化状态是可以改变的，故利用DNA甲基化抑制剂达到防治肿瘤的目的成为可能。
应用推荐