The protein encoded by BRCA1 is involved in DNA repair.
被BRCA1基因编码的蛋白质与DNA修复有关。
It has long been held that there is no DNA repair in mitochondrial.
长期以来,人们一直认为线粒体中不存在DNA的修复。
And in blocking DNA repair you conceivably increase the risk of cancer.
阻止了DNA修复,也就意味着增加了癌症的危险。
This led them to the functional experiments that established its role in DNA repair.
这个现象引导科研人员进行了进一步的实验,以明确其在DNA修复中的作用原理。
Field defects in DNA repair: is loss of MGMT an initial event in colorectal carcinogenesis?
DNA修复的场缺陷:MGMT的丢失是否为直结肠癌发生的初始事件?
Objective:To study the effect of wolfberry fruit on antisenium and the DNA repair of wolfberry fruit.
目的:研究中药枸杞子的抗衰延寿功效及增强DNA修复能力的作用。
Early on, cancer cells typically flourish by disabling DNA repair and ramping up the mutational frenzy.
早前,癌症细胞往往是通过破坏DNA修复功能而快速生长,引发疯狂的突变。
Objective: Much evidence show that tumor development is related to the ability of cell 's DNA repair system.
目的:许多证据表明肿瘤的发生与细胞DNA损伤修复能力下降有密切关系。
Conclusion Inhibition of CRLP may reduce the DNA repair ability through blocking DNA repairing complex forming.
结论CRLP基因的表达受到抑制以后可能通过影响细胞DNA修复能力降低细胞抗紫外杀伤的能力。
This paper is to report the experimental results concerning the effect of PHA stimulation on lymphocyte DNA repair.
本文报道PHA刺激对淋巴细胞DNA修复的影响的实验结果。
In experiments on mice with lung tumours the researchers showed that blocking a molecule called Cdk1 also stopped DNA repair.
对有肺癌的实验鼠进行实验,研究发现依赖性蛋白激酶1 (Cdk1)让DNA停止修复。
PARP1 is an enzyme that is one of the "first responders" to DNA damage and is involved in several DNA repair machineries.
PARP1是一种酶,它是对DNA损伤做出最早反应的分子之一,与多种DNA修复机制有关。
These drugs exploit weaknesses in cells' DNA repair machinery, and are already used to treat some cases of ovarian cancer.
这些药物利用细胞的DNA修复机制的缺陷,并已经用于治疗卵巢癌的一些病例。
AIM: To study the effect of medlar on DNA repair after injury, and investigate the pharmacological role of medlar against aging.
目的:检测枸杞子对遗传物质DNA受损后修复的作用,探讨枸杞子在抗衰老中的药理作用。
Reported effects of some oncogenes, tumour suppressor genes and DNA repair genes on sensitivity of cells to ionizing radiation are reviewed.
综述了一些癌基因、肿瘤抑制基因和DNA修复基因对细胞电离辐射敏感性的影响。
In response to DNA damage, the complex cellular mechanisms including cell cycle arrest, transcription induction and DNA repair are activated.
为了应对DNA损伤,细胞有一套复杂的机制,包括细胞周期停滞,诱导转录和DNA修复被激活。
09052109 in patients with Fanconi anaemia (FA), one of the DNA repair mechanisms that normally protects us against cancer no longer works adequately.
范可尼贫血(FA)病人是由于DNA修复机制——一种有助于我们抵抗癌细胞增长的正常机制——不再充分发挥作用而引起的。
The results confirmed that the alcohol (ethanol) was being converted to acetaldehyde, causing DNA damage and switching on the cell's DNA repair genes.
结果表明,酒精(乙醇)转换成乙醛后破坏dna,激活细胞内dna的修复基因。
Objective To explore the association between genetic polymorphisms of DNA repair genes XRCC1 , XRCC3 and susceptibility to chronic benzene poisoning.
目的探讨DNA修复基因XRCC1、XRCC3多态性与慢性苯中毒遗传易感性的关联及其与慢性苯中毒潜伏期的关系。
Objectives to detect the expression of DNA repair genes in primary glioma tissues by low-density array, and to analyze the significance of the expression.
目的运用低密度表达谱芯片检测人脑原发胶质瘤组织中DNA损伤修复基因的表达情况,进一步分析其表达变化的意义。
One line of evidence supporting the connection is that defects in certain genes needed for DNA repair produce maladies that mimic those of accelerated aging.
支持这种关系的证据是需要修复的特定基因的损伤产生疾病例如加速衰老。
Arsenic causes carcinogenicity on human skin through inhibiting the expressions of MGMT, XRCC1 and influencing the genetic stability and the DNA repair function.
砷可能通过抑制砷中毒患者皮肤组织中MGMT、XRCC1等DNA修复基因的表达,影响基因组d NA稳定性和DNA修复功能而导致对皮肤的致癌作用。
In addition, the research has also identified a promising protein marker involved in DNA repair in cancer cells that predicts resistance to chemotherapy in tumours.
此外,还发现了一种与肿瘤细胞DNA修复有关的蛋白标记物,可预测肿瘤对化疗的敏感性。
Objective To investigate the association of polymorphisms of metabolic and DNA repair enzyme genes and DNA damage in peripheral blood lymphocytes in coke-oven workers.
目的研究外源性化学物代谢酶和DNA损伤修复酶基因多态性与焦炉作业工人外周血淋巴细胞DNA损伤易感性的关系。
To figure out why, the researchers analyzed which genes were being transcribed more as resistance developed, and identified several that are involved in DNA repair pathways.
为了找出原因,研究员分析了那种基因在获得耐药性是转录的最多,辨别几种参与了DNA修复途径。
The genetic polymorphisms of the DNA repair gene XRCC1 might contribute to the susceptibility to gastric cancer and interact with smoking, drinking, pickle, engorgement.
XRCC1基因多态性可能会增加胃癌的易感性,并可能与烟酒嗜好、腌制食品及暴饮暴食存在协同作用。
Women were more likely to have breast cancer if they were older, had a family history of breast cancer, had no history of breastfeeding and had lower DNA repair capacity.
如果女性年龄大,有乳腺癌家族史,无哺乳史和较低的DNA修复能力,那么这些人可能会发生乳腺癌。
In addition, it has been found that DNA repair system is not only associated with cellular sensitivity to chemotherapy, but also with cellular sensitivity to radiotherapy.
另外,研究发现,DNA修复系统的功能不仅是决定肿瘤细胞对化疗药物敏感性的重要因素,而且也直接影响到肿瘤细胞的放射敏感性。
To ensure genome integrity and prevent aneuploidy, eukaryotes have evolved an integrated protective mechanism, including cell cycle control, checkpoint control, and DNA repair.
真核生物对维持基因组的稳定性及防止非整倍体的产生,有其一套完整的保护机制,即细胞周期调控、检验点调控以及对损伤DNA的修复。
To ensure genome integrity and prevent aneuploidy, eukaryotes have evolved an integrated protective mechanism, including cell cycle control, checkpoint control, and DNA repair.
真核生物对维持基因组的稳定性及防止非整倍体的产生,有其一套完整的保护机制,即细胞周期调控、检验点调控以及对损伤DNA的修复。
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