To explore the relationship between polymorphisms of DNA repair gene XRCC1 and susceptibility to radiation injury.
研究DNA修复基因XRCC1多态性与辐射损伤易感性的关系。
The genetic polymorphisms of the DNA repair gene XRCC1 might contribute to the susceptibility to gastric cancer and interact with smoking, drinking, pickle, engorgement.
XRCC1基因多态性可能会增加胃癌的易感性，并可能与烟酒嗜好、腌制食品及暴饮暴食存在协同作用。
Objective To investigate the expression of DNA repair gene family members of ERCC1, RRM1 and BRCA1 in tissues of advanced non-small cell lung cancer (NSCLC), and explore its clinical significance.
目的探讨晚期非小细胞肺癌(NSCLC)组织中DNA修复基因家族成员ERCC1、RRM1和BRCA1的表达及其临床意义。
Normally zebrafish, which carry the same p53 gene as humans, can survive low doses of radiation, which causes damage to the DNA, because the gene steps in to repair that damage.
在通常情况下，像人类一样携带相同p 53基因的斑马鱼可以承受小剂量的放射，放射会对DNA造成损坏，而基因会加入对损坏的修复。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
Objective To screen DNA replication, and damage repair genes associated with benzene poisoning by using gene expression profile analysis.
目的筛选与苯中毒有关的DNA复制及损伤修复基因。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of the DNA damage response and DNA repair.
乳腺癌易感基因，BRCA1，编码一种E3泛素连接酶，BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
AIM: To investigate the expression of nucleotide excision repair gene ERCC1 and its relationship with PAH (polycyclic aromatic hydrocarbons) -dna adducts in lung cancer tissues.
目的：探讨核苷酸切除修复基因ERCC1在肺癌中的表达及其与多环芳烃(PAH) -DNA加合物的关系。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of DNA damage response and DNA repair.
乳腺癌易感基因，BRCA1，编码一种E3泛素连接酶，BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogene expression, DNA synthesis and repair systems, and cell apoptosis.
抑癌基因p53编码转录因子p53蛋白在调控癌基因表达、dna合成和损伤修复以及细胞凋亡中起关键作用。
The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogene expression, DNA synthesis and repair systems, and cell apoptosis.
抑癌基因p53编码转录因子p53蛋白在调控癌基因表达、dna合成和损伤修复以及细胞凋亡中起关键作用。
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