Grapefruit and pomelo aren't the only fruits that affect drug metabolism.
葡萄柚和柚子不是影响药物代谢的唯一水果。
Cytochrome P450 enzyme are an important enzyme family in drug metabolism.
色素氧化酶p 450是药物代谢中的一个重要的酶系。
CYP3A29 is the most important key enzyme for drug metabolism in pig's liver.
CYP3A29是猪肝脏最重要的药物代谢关键酶。
When renal function declined, drug excretion slow, and drug metabolism altered.
肾功能减退时，不但药物排泄缓慢，而且药物代谢也会发生改变。
METHOD:The probe drugs of drug metabolism, methods of phenotype and related factors were reviewed.
方法：综述近几年具遗传多态性代谢酶的探针药物、代谢分型方法以及影响因素。
The application of HPLC-NMR in drug metabolism, natural products analysis and food analysis were reviewed.
综述了目前HPLC-NMR联用技术在药物代谢研究，天然产物分析以及食品分析等方面的应用。
CONCLUSION In situ liver perfusion is an appropriate organ model for drug metabolism and disposition research.
结论大鼠原位肝灌流是良好的整体器官药物代谢模型，是体外实验有力的补充。
Courses of study include mammalian physiology and pharmacology, drug metabolism, neural control, oncology, and other topics.
学习课程包括哺乳动物生理学，制药学，药品的新陈代谢，神经控制，肿瘤学和其他学科。
CYP450 is regulated by genetic genes. Once the gene mutates, the CYP450 enzyme that coded and the drug metabolism then will change.
CYP450的合成受着遗传基因的调控，一旦基因发生变异，它所调控合成的CYP450酶及酶所催化的药物代谢即发生变化。
This review provides a better understanding of the cytochrome P450 system with a focus on those enzymes most involved in drug metabolism.
这次综述提供了一个对大多数药物代谢有关的酶为重点的细胞色素P 450系统的了解。
Primary cultures of hepatocytes have been extensively used for evaluation of drug metabolism, drug-drug interactions and drug hepatotoxicities.
体外培养的原代肝细胞被广泛用于药物代谢、药物间相互作用和药物肝毒性的研究。
The process of drug metabolism is such which may exert influence on the development of the effectiveness and the production of the toxicity of drugs.
药物代谢过程是影响药物发挥作用及产生毒性的过程。
Predicting of drug metabolism in humans based on animal experiments is complicated by species differences in the catalytic properties of these enzymes.
根据动物实验来预测人体的药物代谢时，代谢酶的种属差异性会使这项研究工作变得非常困难。
Pharmacogenomics testing analyzes genes that are related to drug metabolism & activity, which can influence how a person responds to certain medications.
药物基因组检测是对影响药物代谢和活性的基因进行检测和分析，这些基因会影响个体对药物的反应。
From the handful of studies on the effects of pomelo on drug metabolism, it looks like pomelo and pomelo juice act much like grapefruit and grapefruit juice.
根据少数关于柚子对药物代谢影响的研究，看起来柚子和柚子汁像葡萄柚和葡萄柚汁一样起作用。
Balaglitazone has been evaluated in a series of preclinical efficacy pharmacology, safety pharmacology, pharmacokinetic/toxicokinetic, and drug metabolism studies.
巴格列酮已经经过一系列临床前期药效药理学、安全药理学、药代动力学或毒性动力学和药物代谢研究的评估。
It was suggested that Bama miniature pigs and Guizhou miniature pigs were both feasible for experimental animal model for evaluating drug metabolism in some degree.
提示巴马香猪、贵州小型香猪作为药物评价的实验动物具有一定可行性。
Drug metabolism enzymes (DME) play a significant role in drug detoxification and activation, which exert important effect on drug efficacy and sensitivity to toxicity.
药物代谢酶(DME)在药物代谢解毒和药物代谢活化中起着重要的作用，对组织器官的药物效应和毒性的易感性产生重要影响。
There are differences in drug metabolism, differences in drug clearances and when they interact like that you can have frightening problems in terms of adverse reactions.
药物的代谢和清除存在差异且当他们像这样相互时，就不良反应而言可能会出现可怕的问题。
CONCLUSION Active recombinant human CYP2B6 obtained using baculovirus expression system will facilitate further examination of the role of this enzyme in drug metabolism.
结论杆状病毒表达系统能成功表达有活性的CYP2B6重组酶，可用来进一步研究在药物代谢中的作用。
The expressions of the various genes modulated cell growth and proliferation, apoptosis, cell cycle, stress response, transporters, chaperones, transcription regulation and drug metabolism.
差异表达的基因的功能涉及细胞生长增殖调控、凋亡、细胞周期、应激反应、转运及代谢酶等方面。
The adverse drug interactions can be avoided by knowing the enzymology basis of drug metabolism, common substrates, inductors, inhibitors involved and using the same kind of drugs rationally.
认识药物代谢的酶学基础，了解药酶的常见底物、诱导剂和抑制剂，合理选用同类药品，能避免有害药物代谢性相互作用的发生。
This review includes basic concepts of pharmacogenomics, heterogeneity of hypertension and antihypertensive drug responses, genes associate with drug metabolism, and individualized drug therapy.
本文综述了药物基因组学的基本概念、高血压病和抗高血压药物反应异质性、与药物新陈代谢相关的基因、个体化治疗等方面的应用情况。
Choosing the suitable drugs and dosages according to cytochrome P450 and drug metabolism would improve the pharmacotherapy efficacy and reduce the adverse drug reaction and toxic effect of drugs.
根据细胞色素P 450和药物的生物转化来选择合适的药物及合适的剂量将有助于最大程度地提高药物治疗效应，同时减少药物不良反应和毒副作用。
Mice transplanted with HEALs exhibit humanized liver functions persistent for weeks, including synthesis of human proteins, human drug metabolism, drug–drug interaction, and drug-induced liver injury.
这组作者报告说，这些肝脏有效地移植了过去，而且这些小鼠在数周时间里展现出了人类肝脏的功能，包括人类蛋白质的合成以及人类药物代谢。
The solubility, stability in gastrointestinal tract, membrane permeability and presystemic metabolism of drugs were the major factors on oral drug absorption.
药物的溶解性，在胃肠道中的稳定性，膜的通透性和全身代谢是影响口服药物吸收的主要因素。
There's a growing awareness that we need to more carefully consider obesity and other factors that affect drug absorption, distribution, metabolism and other factors.
人们越来越多的意识到，其应该认真研究肥胖以及其他因素对药物的吸收、分布、代谢和其他方面的影响。
Decreased peripheral blood flow also alters drug distribution and metabolism.
外周血流减少也会改变药物的分布和代谢。
Decreased peripheral blood flow also alters drug distribution and metabolism.
外周血流减少也会改变药物的分布和代谢。
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