Enantiomer separation is one of the most important research fields of chiral technology.
手性拆分是手性技术的重要研究方向。
The enantiomer that rotates the plane to the right is referred to as the dextrorotatory.
使平面向右旋转的对映体,称为右旋对映体。
The enantiomer of some chiral drugs has different pharmacology activity and different applying.
手性药物对映体具有不同的药理活性和不同的用途。
It was found that resolution of enantiomer of neutral compound was enhanced by adding certain amount of methanol.
同时发现,一定含量的甲醇可以提高中性化合物对映体分离度。
In response to the best conditions, the reaction rate achieved 98.5% and the enantiomer excess value achieved 100%.
在最佳反应条件下反应的产率达到98.5%,产物的对映体过量值达到100%。
Objective: to establish an HPLC method for the resolution of metoprolol enantiomer using chiral mobile phase additives.
目的:建立hplc手性流动相添加剂法拆分美托洛尔对映体的方法。
The configuration inversion can offer the desired enantiomer in high efficiency, but with certain limitation in application.
构型反转能够直接得到所需要的对映体,效率高,但其应用局限性较大;
Chemical synthesis course is simple which can be industrialized, the product is DL-enantiomer, it is difficult to separate and get rid of D-Theanine.
而化学合成法制备茶氨酸,操作相对简单,易于工业化生产,但产品多为D -、L -的混旋体,D -茶氨酸的分离与去除具有较高的技术难度。
The method and technical development of acetonation of hexabasic alcohol, and its application in the synthesis of one enantiomer of drugs were reviewed.
论述六元糖醇丙酮化作用的方法和工艺进展 ,以及其在合成光活性单一对映体药物中的应用。
The influences of the composition of mobile phase, the flow rate, the temperature and the injected quantity on the enantiomer rententivity and selectivity were examined and discussed.
考察了流动相组成、流速、进样量和温度等因素对对映体分离的影响。
METHODS: Comprehensivelly analyzing the status of the wildlife and the planting herb resource of galantamine, and the progress of synthesizing racemized galantamine and it's enantiomer.
方法分析加兰他敏野生资源分布与人工栽培,及其外消旋体与对映体的化学合成进展状况。
The enantiomer-specific structure of local anaesthetics has large impact on the pharmacokinetic process of these drugs, including absorption, protein-binding ratio, metabolism, and so on.
药物对映体结构特异性对局麻药药代动力学的各个过程都有着很大影响,包括药物的吸收、蛋白结合率、代谢等。
Many methods were investigated for the synthesis of the single enantiomer of the chiral intermediate, including chemical resolution, chemical asymmetric synthesis and chemo-enzymatic synthesis.
研究人员采用多种方法合成单一构型的地尔硫卓手性中间体,其中包括化学拆分、化学不对称合成以及化学-酶法合成等方法。
From 1-phenyl-2-propylamine, selegiline hydrochloride, an anti-Parksins drug, was synthesized via N-methylation, enantiomer separation, N-alkylation and salt formation with an overall yield of 42.2%.
以1- 苯基- 2-丙胺为原料,经N- 甲基化、拆分、N-炔基化、成盐共4步反应合成盐酸司来吉兰,总收率为42。
From 1-phenyl-2-propylamine, selegiline hydrochloride, an anti-Parksins drug, was synthesized via N-methylation, enantiomer separation, N-alkylation and salt formation with an overall yield of 42.2%.
以1- 苯基- 2-丙胺为原料,经N- 甲基化、拆分、N-炔基化、成盐共4步反应合成盐酸司来吉兰,总收率为42。
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