Objective:To be improved synthesis of ganciclovir.
目的：对更昔洛韦的合成工艺进行改进。
Ganciclovir was effective for treatment of CMV infection.
更昔洛韦能够有效的治疗CMV感染。
Objective: Verify the clinical effect of Ganciclovir Eye Drops.
目的：验证更昔洛韦滴眼液的临床应用效果。
Ganciclovir is effective in the treatment of symptomatic CMV infection.
更昔洛韦治疗症状性CMV感染效果较好。
Ganciclovir was used to prevent CMV infection before the transplantation.
移植前采用更昔洛韦预防CM V感染。
CMV infection may be treated with drugs such as ganciclovir, valganciclovir and forscarnet.
巨细胞病毒感染可使用药物治疗，如更昔洛韦，缬更昔洛韦和膦甲酸。
Objective:To investigate the efficacy of ganciclovir in the treatment of children with varicella.
目的：探讨更昔洛韦在儿童水痘治疗中的临床疗效。
To study on the the effect of ganciclovir combined with cimetidine on infants with rotavirus enteritis.
研究更昔洛韦配伍西咪替丁治疗婴幼儿轮状病毒性肠炎的疗效。
Objective: To explore the effect of ganciclovir and cimetidine therapy on infants with rotavirus enteritis.
目的：探讨更昔洛韦与西咪替丁联合治疗婴幼儿轮状病毒肠炎的效果。
The invention also relates to a preparation method of the Ganciclovir freeze-dry preparation for injection.
本发明还涉及该注射用更昔洛韦冻干制剂的制备方法。
Objective To observe the clinical therapeutic effects of Ganciclovir on the children with virus encephalitis.
目的观察更昔洛韦治疗小儿病毒性脑炎的临床疗效。
Conclusion: Ganciclovir is the most effective and safe in treatment of children with viral encephalitis caused by EBV.
结论：更昔洛韦治疗儿童EB病毒性脑炎效果明显而安全。
Conclusion The proposed method is simple, conventinent and is suitable for the quality control of Ganciclovir for injection.
结论该方法简便、可行，可用于检测注射用更昔洛韦的含量。
Objective To observe the clinical curative effect of ganciclovir for the treatment of children with infectious mononucleosis .
目的观察更昔洛韦治疗儿童传染性单核细胞增多症的临床疗效。
The combined filtrates from filtration and the washings are concentrated and lyophilized to isolate ganciclovir L-valine ester.
合并滤液和洗涤液浓缩并冻干以分离更昔洛韦L -缬氨酸酯。
Step II: Ganciclovir with a protected 2-amino group and one aliphatic hydroxy group protected is subjected to de-protection of the amino group.
第二步：2-氨基和一个脂链羟基被保护的更昔洛韦要脱除氨基保护。
Ganciclovir could be purified to more than 99.0%(HPLC) by a combination of acetone, acetic acid and water in 83.3% recovery as compared with 30% one when using water or methanol as solvent.
相比目前使用的水或甲醇溶剂纯化收率30％，发现以丙酮、乙酸、水的溶剂体系，精制更昔洛韦收率可显著提高到83.3％，高效液相色谱（HPLC）分析，产品纯度达到99.0％以上。
Conclusions 0.2% ganciclovir in-situ gelling eye drops significantly increases the drug penetration into cornea and aqueous humor, and prolongs the residence time in cornea and aqueous humor.
结论更昔洛韦原位胶化滴眼液同一般滴眼液相比，明显延长药物在眼部的滞留时间，增加角膜组织和房水中的药物浓度。
Conclusions 0.2% ganciclovir in-situ gelling eye drops significantly increases the drug penetration into cornea and aqueous humor, and prolongs the residence time in cornea and aqueous humor.
结论更昔洛韦原位胶化滴眼液同一般滴眼液相比，明显延长药物在眼部的滞留时间，增加角膜组织和房水中的药物浓度。
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