GJB2 gene knockout mice led to death during embryonic period.
GJB2基因敲除小鼠在胚胎期致死。
BPOZ gene knockout leads to es cell growth suppression and has no significant influence on es cell differentiation.
BPOZ基因剔除使es细胞生长受抑，对ES细胞分化发育没有明显影响。
Objective Serum lipid and histopathological status were observed in apoE gene knockout mice of different genders and ages.
目的观察我部饲养的不同年龄、不同性别的载脂蛋白E基因缺陷小鼠的血脂及病理组织学状况。
Objective: To study the effects of water extract from Paris Polyphylla Smith on advanced plaques in ApoE gene knockout mice.
目的研究蚤休水提液对载脂蛋白E基因敲除小鼠晚期斑块的影响。
The widespread use of gene knockout technology promotes the course of the research of gene function in post genomic era greatly.
基因敲除技术的广泛应用，极大地推动了后基因组时代对于基因功能研究的进程。
In this paper, the basic principles of gene knockout, several common techniques and their application in microbial breeding were introduced.
论述了基因敲除的基本原理、几种常用技术及该项技术在微生物育种方面的应用。
In addition, several useful laboratory techniques, e. g. small RNA interference and gene knockout are comprehensively introduced during the lecture.
同时，课程也将对RNA干扰和基因敲除等重要的实验技术的原理及应用作专题介绍。
Objective: To establish a highly efficient production system of chimeras by perfecting and normalizing the key steps of technology system of gene knockout mice.
目的：完善和规范基因剔除小鼠技术体系的关键技术环节，建立一套高效的嵌合体制备体系。
This paper introduced the principle, the targeting strategies, the screening mechanism and the commonly method in animals, plants and micro-organisms of gene knockout.
本文简述了基因敲除技术的基本原理、打靶策略、筛选机制，在动植物和微生物中常用的基因敲除方法以及基因敲除的应用。
The technology system of gene knockout mice is a most urgently needed technique in the life science research, especially in human genomic project and medical animal models research.
基因剔除小鼠的技术体系是生命科学研究，尤其是人类基因组计划和医学实验动物模型等领域所急需的关健技术。
These knockout procedures are now commonly done in mice and rats, and three researchers earned a Nobel prize in 2007 for developing this method, called "gene targeting".
这种基因敲除程序现在已经被普遍用于小鼠和大鼠，3名研究人员因为发明了这种“基因打靶”技术获得了2007年的诺贝尔奖。
Note: the underlined part is the homologous sequence of the target knockout gene.
注：下划线部分为目的基因同源臂序列。
Objective To construct a new retroviral vector with double-suicide genes and knockout-inducible SV40T gene, with the aim of optimizing immortalization of hepatocytes.
目的构建携带双自杀基因且可诱导敲除SV40T的逆转录病毒载体，优化目前的肝细胞永生化。
Objective To delve into the relationship of blood-lipid to serum bilirubin in ApoE gene-knockout mice.
目的探讨动脉粥样硬化小鼠血脂与血清胆红素之间的关系。
Transgenic and knockout mouse lines are now a major method to study the effects of mutated gene and expression alternations in vivo.
公司用来研究变异基因和交替表达效果的主要方法。
In focal ischemia, intracerebroventricular injection of ASIC1a blockers, or knockout of the ASIC1a gene protects the brain from ischemic injury.
在缺血中，脑室内注射ASIC 1a阻滞剂、或干扰asic 1a基因性缺血性损伤，实现脑保护作用。
In focal ischemia, intracerebroventricular injection of ASIC1a blockers, or knockout of the ASIC1a gene protects the brain from ischemic injury.
在缺血中，脑室内注射ASIC 1a阻滞剂、或干扰asic 1a基因性缺血性损伤，实现脑保护作用。
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