Conclusion: D12S1686 is such a valuable genetic marker that it can be used to gene linkage analysis and population genetics research.
结论D 12s1686位点具有较高的杂合度和多态信息含量，在基因连锁分析和群体遗传学研究中具有重要的应用价值。
Linkage disequilibrium analysis is a effective way to identify the function of the of the gene (or targeted high-resolution QTL).
连锁不平衡分析是对基因(或已定位的高分辨率QTL)的功能进行鉴定的有效方法。
Objective:The linkage analysis of gene polymorphism and diseases is the common method to study the molecular biological base of multigenic diseases.
目的：基因多态和疾病的连锁分析是目前研究多基因疾病分子生物学基础的常用方法。
The disease gene is exactly located on the chromosome 5 and chromosome 12 through parameter and non-parameter linkage analysis.
综合运用参数和非参数连锁分析，将致病基因定位到5号染色体和12号染色体上。
Conclusions it suit to the small pedigree data. Multipoint linkage analysis can not only calculate the recombination and map distance, but also localize the disease gene to one side of the marker.
结论适用于小家系资料的多位点连锁分析，不仅能算出致病基因与标记的重组率和遗传距离，而且能把致病基因定位至遗传标记的一侧。
Results the multipoint linkage analysis could more accurately localize the disease gene than the two_point linkage analysis.
结果多位点连锁分析比两位点连锁分析基因定位更精确。
Results the multipoint linkage analysis could more accurately localize the disease gene than the two_point linkage analysis.
结果多位点连锁分析比两位点连锁分析基因定位更精确。
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