The expression of TCR function depend on the gene rearrangement during ontogeny in nor-mal t cell.
细胞抗原受体(TCR)功能的表达有赖于该基因在正常T淋巴细胞发育过程中的重排。
Immunohistochemistry and gene rearrangement are important detective methods for brain lymphoma diagnosis.
免疫组化及基因重排是诊断脑淋巴瘤重要工具。
The positive rate of T-cell receptor gene rearrangement was 81.3%, and was independent of the histological features.
细胞受体基因重排的阳性率为81.3%,阳性率与疾病分期无关。
Clonal immunoglobulin heavy chain gene rearrangement can be used as a effective diagnostic molecular marker for B-NHL.
克隆性免疫球蛋白重链基因重排检测可以作为诊断恶性B细胞性非霍奇金淋巴瘤的有效分子标志。
Objective: in order to determine the significance of gene rearrangement in malignant lymphocytic proliferation disease.
目的:对淋巴细胞恶性增殖病进行研究。
Methods: to read the related literatures then to review and comment the B lymphocyte development and BCR gene rearrangement.
方法:通过相关文献的阅读,综合评述B细胞发育与BCR基因重排。
Conclusion: B lymphocyte development and BCR gene rearrangement is an ordered sequence. However, a lot of events in this procedure are unclear.
结论:B细胞发育及BCR基因重排是一个密切相关的十分有序的过程,但仍有许多问题未弄清楚。
Objective To evaluate the diagnostic significance of detecting serum-DNA concentration and clonal gene rearrangement in lymphogenous malignant patients.
目的探讨血清游离DNA含量及其克隆性重排基因检测在淋巴系统恶性肿瘤诊断中的价值。
The detection of TCR gene rearrangement has an important role in the study of the pathogenesis, classification, diagnosis and monitoring of prognosis of CTCL.
细胞受体基因重排的检测在皮肤T细胞淋巴瘤的发病机制研究、分类、诊断、判断预后上有重要的作用。
Objective To study the clinicopathological features, the immunophenotyping, the gene rearrangement and the prognosis of subcutaneous panniculitis-like T-cell lymphoma (SPTCL).
目的研究皮下脂膜炎样T细胞淋巴瘤的临床病理特征、免疫表型、基因重排和预后。
The results suggested that these highly specific gene rearrangement would contribute to the detection of minimal residual Leukemia cells and a part of the evolutionary clone could be distinguished.
其独特的基因重排方式具高度特异性,有助于微小残留病的检测及部分演化克隆的识别。
T cell receptor (TCR)gene rearrangement is an important event in T cell ontogeny that enables T cells to specifically recognise antigens, and any dysregulation in this process may result in diseases.
细胞在成熟过程中通过T细胞表面受体基因重排,从而具有特异性识别抗原的能力,在这一过程中的任何失调都会导致疾病。
Conclusion 1. EGFR gene amplification and rearrangement rarely occur in human malignant hematologic disorders.
结论EGFR基因的扩增与重排较少发生在人类血液系统恶性疾患中。
Mechanical stimulation can induce the rearrangement of the cytoskeleton, and the signals are transduced and transformed by the second messagers, finally resulting in the changes of gene expression.
力学刺激可引起骨架纤维重排并可借助第二信使将力学信号传递并转换,最终调节基因的表达。
Mechanical stimulation can induce the rearrangement of the cytoskeleton, and the signals are transduced and transformed by the second messagers, finally resulting in the changes of gene expression.
力学刺激可引起骨架纤维重排并可借助第二信使将力学信号传递并转换,最终调节基因的表达。
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