This paper briefly reviews the hepatic stellate cells (HSC) activation and proliferation-related signal transduction pathway and explores the role in the pathogenesis of liver fibrosis.
本综述以肝星状细胞激活与增殖相关信号转导通路为中心,探讨其在肝纤维化发病作用方面的作用机制。
Objective: To explore the mechanism of JNK pathway regulating proliferation of hepatic stellate cells(HSC) stimulated by acetaldehyde.
目的:初步探讨JNK信号通路调控乙醛刺激的大鼠肝星状细胞(HSC)增殖的分子机制。
Objective To investigate the effects of demethylbellidifolin(DMB) on activation of hepatic stellate cells(HSC) and its underlying mechanism.
目的研究去甲基雏菊叶龙胆酮(DMB)对肝星状细胞(HSC)活化的影响及其机制。
Objective To investigate the anti-oxidative stress effects of Taurine on rat hepatic stellate cells (HSC) cultured in vitro.
目的:探讨牛磺酸在体外培养的大鼠肝星状细胞(hsc)的抗氧化作用。
Methods HSC-T6 hepatic stellate cell line was chosen as the study model of the activated hepatic stellate cells.
方法采用HSC - T6肝星状细胞系作为活化的肝星状细胞的研究模型。
Aim to study the effects of total extract of astragalus (TEA) on activating the primary cultured hepatic stellate cells (HSC) and synthesizing collagen.
目的研究黄芪总提物(TEA)对体外肝星状细胞增殖和产生胶原的影响。
Methods HSC-T6 rat hepatic stellate cell line was chosen as the study model of the activated hepatic stellate cells.
方法采用HSC-T6肝星状细胞系作为活化的肝星状细胞的研究模型。
AIM: To activate hepatic stellate cells (HSC) in vitro in precision-cut liver slices (PCLS) stimulated by acetaldehyde for studying and screening anti-fibrotic drugs.
目的:在精密肝切片中利用乙醛激活肝星状细胞,建立一种星状细胞激活的体外模型,为研究和筛选阻抑肝纤维化发生的药物奠定基础。
Aim: to investigate the effects of hepatocyte line and interleukin-10 (IL-10) on the proliferation, activation and apoptosis of primary hepatic stellate cells (HSC).
目的研究大鼠肝细胞及白细胞介素- 10 (IL - 10)对原代肝星状细胞(hsc)增殖、活化及凋亡的影响,并探讨其可能机制。
Aim: to investigate the effects of hepatocyte line and interleukin-10 (IL-10) on the proliferation, activation and apoptosis of primary hepatic stellate cells (HSC).
目的研究大鼠肝细胞及白细胞介素- 10 (IL - 10)对原代肝星状细胞(hsc)增殖、活化及凋亡的影响,并探讨其可能机制。
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