Objective To study the clinic features and the mechanism of skin damage induced by high-dose methotrexate (HD-MTX).
目的了解大剂量氨甲蝶呤(HD - MTX)化疗引起皮肤损伤的临床特征，并探讨其发生机制。
Objective To discuss the practicability of high-dose methotrexate (HD-MTX) in treatment of acute lymphoblastic leukemia (ALL) in children in basic-level hospitals.
目的探讨大剂量甲氨蝶呤(HD -MTX)治疗急性淋巴细胞白血病(all)在基层医院的可行性。
Conclusion High-dose methotrexate combined with AT-1258 chemotherapy appeared to be an effective and safe regimen for patients with refractory or relapsed lymphoma.
结论大剂量甲氨喋呤联合消瘤芥治疗复发难治性恶性淋巴瘤是一种安全有效的方案。
Objective To explore different doses of calcium 5-formyltetrahydrofolate (CF) for protecting enteral mucosa after chemotherapy of high-dose methotrexate (HD-MTX) in rats.
目的探讨不同剂量四氢叶酸钙(CF)对大剂量甲氨蝶呤(HD -MTX)化疗大鼠肠黏膜的保护作用。
OBJECTIVE: to improve the efficacy and safety of high dose methotrexate (HDMTX) chemotherapy in the treatment of children with acute lymphoblastic leukemia through blood concentration monitoring.
目的：通过血药浓度监测，提高对小儿急性淋巴细胞白血病大剂量甲氨蝶呤化疗的有效性和安全性。
RESULTS The pharmacokinetics of high dose methotrexate were described by a two-compartment model.
结果大剂量甲氨蝶呤化疗符合二室模型分布特征。
Objective:To analyse the adverse drug reaction of high dose methotrexate (HD-MTX) in treatment of childhood acute lymphoblastic extramedullary leukemia (ALL).
目的：剖析比拟出口与国产甲氨蝶呤（HD-MTX）在预防治疗儿童急性淋巴细胞髓外白血病进程中不良反响的发作率。
Objective:To analyse the adverse drug reaction of high dose methotrexate (HD-MTX) in treatment of childhood acute lymphoblastic extramedullary leukemia (ALL).
目的：剖析比拟出口与国产甲氨蝶呤（HD-MTX）在预防治疗儿童急性淋巴细胞髓外白血病进程中不良反响的发作率。
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