Integrase inhibitors 2007 integrase inhibitors interfere with the integrase enzyme, which HIV needs to insert its genetic material into human cells.
整合酶抑制剂；首次获准：2007年；抗病毒方式：整合酶抑制剂干预了整合酶酵素，艾滋病病毒正是通过整合酶酵素将自己的遗传物质传到人类细胞。
Objective: To rationally design new inhibitors of HIV-1 integrase.
目的：合理设计新的HIV-1整合酶抑制剂。
Because of the special function of HIV-1 integrase, it has become one of focuses of anti-AIDS drug design.
由于HIV - 1整合酶的特殊功能，它已成为抗艾滋病药物设计工作的焦点之一。
Aim To synthesize a series of new caffeic acid derivatives and test their HIV-1 integrase inhibitory activities.
目的合成新型咖啡酸衍生物并测定其抑制HIV 1整合酶活性。
The application value of each representative system was evaluated to provide some guidance for the platform established for the drug design and screening of HIV-1 integrase inhibitors.
给出了各个代表性体系的应用价值。旨在对HIV - 1整合酶抑制剂药物设计及筛选平台的建立提供一定的参考。
Terphenyllin has not been extensively studied but has been reported to exhibit anti-oxidative activity, acts as a plant growth inhibitor and shows weak activity against HIV integrase.
三联苯曲菌素还没有被广泛的研究但已报道显示其有抗氧化的活性，做为一种植物生长抑制剂，也显示了弱的抗HIV整合酶的活性。
HIV-1 integrase (in) integrates viral DNA into host cells through two steps metal ions-dependent reactions.
HIV - 1整合酶(IN)通过依赖金属离子的两步反应将病毒DNA整合入宿主细胞中。
Two are "integrase inhibitors" that block the HIV genetic material from attaching to the host cell's DNA.
其中两种药物是“整合?抑制剂”，它可以阻止艾滋病病毒的遗传物质附加到宿主细胞的DNA中。
Two are "integrase inhibitors" that block the HIV genetic material from attaching to the host cell's DNA.
其中两种药物是“整合?抑制剂”，它可以阻止艾滋病病毒的遗传物质附加到宿主细胞的DNA中。
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