Conclusion HSV-TK/GCV gene therapy system may provide a new therapeutic approach for treatment of osteosarcoma.
结论HSV-TK/GCV基因治疗系统可为骨肉瘤的治疗提供新途径。
The use of negative selection gene (HSV-tk) results in 7-fold increase at selection efficiency.
负向选择系统的应用使同源重组事件的富集效率提高了7倍。
Conclusion: transfection of gastric carcinoma with HSV-TK has higher transfection efficiency. MKN28TK cells are significantly sensitive to GCV.
结论：逆转录病毒介导的HSV -TK系统对人胃癌细胞有较高的转染效率，GCV对转染阳性的胃癌细胞有显著的杀伤作用。
Conclusion: transfection of gastric carcinoma with HSV-TK has higher transfection efficiency. MKN28TK cells are significantly sensitive to GCV.
结论：逆转录病毒介导的HSV -TK系统对人胃癌细胞有较高的转染效率，GCV对转染阳性的胃癌细胞有显著的杀伤作用。
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