The retrovirus carrying IL-18 gene was used to infect murine liver cancer cell MM45T.
包装成逆转录病毒,感染小鼠肝癌细胞MM 45t。
To explore the effects of IL-18 gene transfection on the proliferation of C6 glioma cell.
探讨IL-18基因转染对大鼠C6胶质瘤细胞生长特性的影响。
Objective To investigate the serum level of interleukin IL-18 in nasopharyngeal carcinoma.
目的探讨血清白介素- 18的变化与鼻咽癌的关系。
Objective: it is to study the role of IL-18 in the pathogenesis of ulcerative colitis (UC).
前言:目的:探讨IL - 18在溃疡性结肠炎(U C)发病中的作用。
It has been demonstrated that IL-18 exists in cells of human, mammal and some kinds of birds.
目前在分子水平上已经证明,人、哺乳动物和某些鸟类中都有IL-18存在。
Curcumin inhabited expression of IL-18 to inhabite the proliferation of vascular smooth muscle cells.
姜黄素抑制IL-18在血管损伤后的表达,抑制平滑肌的增殖。
Interleukin-18 (IL-18) is a pro-inflammatory factor, and adipose tissue is one of its important sources.
白细胞介素18 (IL - 18)是一种前炎性因子,脂肪组织为其重要来源之一。
Results: IL-12 and IL-18 induced prominent spleen deficiency syndrome similar with that induced by reserpine.
结果:IL - 12及IL - 18引起明显脾虚证的表现,与利血平制作脾虚动物模型组相似。
Objective: To explore the expression of IL-18 and clinical significance in patients with lupus nephritis (LN).
前言:目的:探讨i L - 18在狼疮肾炎(LN)患者血清中的表达及临床意义。
Objective To measure the serum level of interleukin-18(IL-18) in patients with chronic myelocytic leukemia (CML).
目的:检测慢性粒细胞白血病(CML)患者血清IL-18水平。
Results The serum level of IL-18 in tubercular pleurisy sufferer was significant higher than tha tin healthy group.
结果结核性胸膜炎患者血清中IL 18水平显著高于健康对照组。
Results: The D-Gal-treated rats significantly experienced a dynamic escalation of ALT, AST and IL-18 levels(P<0.05).
结果:D-氨基半乳糖造模后,两组大鼠血清ALT,AST和肝匀浆IL-18值呈动态升高(P<0.05)。
A weak anion exchange column was prepared and a separation method of interleukin-18 (IL-18) was developed on the column.
制备了弱阴离子交换整体柱,并建立了白介素18在该柱上分离纯化的方法。
Objective To explore the effect of interleukin-18(IL-18) interference on the acute immunized hepatonecrosis animal model.
目的探讨白细胞介素(IL) 18 抗体干预,了解IL 18 抗体对急性免疫性肝坏死动物模型的影响。
Therefore, IL-18 should be seen as a unique molecule that constitutes a critical link between innate and adaptive immunity.
因此,IL - 18为联系机体天然免疫和获得性免疫的关键活性分子。
Methods The plasma IL-18 in 36 ITP patients and 36 normal controls were detected by enzyme linked immunosorbent assay (ELISA).
方法酶联免疫吸附测定(ELISA)测定血浆IL - 18,对36例itp患者和正常对照组血浆IL - 18的水平进行分析。
Objective: to investigate whether high mobility group box chromosomal protein 1 (HMGB1) can activate macrophages to secrete IL-18.
目的:探讨高迁移率族蛋白1 (HMGB1)能否激活巨噬细胞表达IL - 18及其受体。
Methods An enzyme-linked immunosorbent assay(ELISA)was utilized to detect the levels of IL-18, VEGF in serum of 75 patients with HSP.
方法采用固相酶联免疫分析法检测75例过敏性紫癜患者血清IL-18、VEGF水平。
In recent years studies, it has been shown that IL-18 participated in the genesis of RA, which has become a new hot spot of RA study.
近年发现,白细胞介素- 18可作用于RA发病的多个参与因素,成为研究RA的新热点。
Methods:We use ELISA and Immunohisto-chemistry to observe the level of IL-8 produced and released by SFs stimulated by IL-18 and triptolide.
方法:利用ELISA和免疫组织化学法检测雷公藤甲素和IL-18刺激的滑膜成纤维细胞合成、释放IL-8的水平。
Conclusion the decline of serum level of IL-18 showed lamivudine may regulate the function of immunity and alleviate soakage of inflammation cell in liver.
结论拉米夫定治疗后il - 18水平下降,提示拉米夫定可调节免疫功能,减轻肝脏炎症细胞浸润。
Conclusion: the immune status is low in gastric cancer tissue and it can be conjectured that this phenomenon relates to the deficiency of 4-1bbl and IL-18.
结论:胃癌组织内处于低免疫状态,推测肿瘤细胞免疫逃逸现象可能与4 - 1bbl和IL - 18的缺乏有关。
Some virus genome of vaccinia subgenus in poxvirus encoded IL-18BP gene, which can block IL-18 activity but no sequence similarity to membrane IL-18 receptors.
从羊痘病毒基因组中寻找并扩增羊白细胞介素-18结合蛋白(IL-18BP)基因。
CONCLUSION the level of IL-18 increases obviously on the 1st day of ACI onset and gradually decreases with the extended course of disease and time of treatment.
结论:白细胞介素18水平在发生急性脑梗死第1天时明显升高,随发病和治疗时间的延长,其水平逐渐下降。
Objective To explore potential synergetic effects of interleukin-2 (IL-2) with IL-18 on induction of natural killer (NK) cell activity against myeloma cells in vitro.
目的研究白细胞介素- 2 (IL - 2)和白细胞介素- 18 (IL - 18)诱导自然杀伤(NK)细胞活化和抗骨髓瘤细胞活性的协同作用。
Through the analysis of the software, it could be found that the secondary structure of IL-18 mature peptide has almost unchanged after fusion and remain its bioactivity.
其相应的氨基酸序列经软件分析,并与人il - 18的成熟肽单独的分析结果相比较,发现在二级结构水平几乎没有变化,融合过程未影响IL - 18的活性。
Recently, elevated IL-18 levels were found in serum from some leukemia patients, especially those with acute lymphocytic leukemia (all) and chronic myeloid leukemia (CML).
近来,研究发现急性淋巴细胞白血病(all)和慢性粒细胞白血病(CML)患者血清中il - 18水平高于正常人。
Objective to investigate the changes of interleukin 18 (IL-18) levels in serum in patients with systemic lupus erythematosus (SLE) and its relationship with the activity of SLE.
目的探讨白细胞介素18 (IL - 18)在系统性红斑狼疮(SLE)患者血清中的水平变化及其与SLE活动性的关系。
To study rudimentarily the role of IL-18 in acute immunity hepatic injury, and the important of blocking cascade reaction of cytokines by exerting IL-18 antibody in early stage.
通过动物实验,初步探讨IL-18在急性免疫性肝损伤中的意义,及早期使用IL-18抗体及时阻断细胞因子级联反应对保护肝组织的重要性。
Objective To detect the clinical significance of changes of serum cyclooxygenase-2 (COX-2) activity and interleukin-18 (IL-18) in patients with T2DM diagnosed by the first time.
目的探讨初发2型糖尿病患者外周血中环氧化酶2(COX-2)活性与白介素18(IL-18)含量变化的临床意义。
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