Conclusion IL 18 May play an important role in immune response to human infection with Mycobacterium tuberculosis.
结论IL -18可能在肺结核病人抗结核菌感染免疫中发挥重要作用。
Objective To investigate the effect of interleukin 18 (IL 18) gene transfer on the tumorigenesis of lung carcinoma cell line PG.
目的探讨白细胞介素-18 (IL - 18)基因转导对肺癌细胞系PG细胞肿瘤原性的影响。
To investigate the clinical significance of dynamic change of serum interleukin 18 (IL 18) levels in acute cerebral infarction(ACI) patients.
了解急性脑梗死患者血清白介素-18（IL-18）动态改变的临床意义。
Objective To elucidate the expression and regulation of interleukin 18 (IL 18) in human leukemia cell line J6 1, and investigate its possible role in leukemogenesis.
目的阐明白细胞介素18 (IL 18)在人白血病细胞系J 61的表达与调控，探讨IL 18在白血病发生中的意义。
Conclusion the decline of serum level of IL-18 showed lamivudine may regulate the function of immunity and alleviate soakage of inflammation cell in liver.
结论拉米夫定治疗后il - 18水平下降，提示拉米夫定可调节免疫功能，减轻肝脏炎症细胞浸润。
Results The serum level of IL-18 in tubercular pleurisy sufferer was significant higher than tha tin healthy group.
结果结核性胸膜炎患者血清中IL 18水平显著高于健康对照组。
It has been demonstrated that IL-18 exists in cells of human, mammal and some kinds of birds.
目前在分子水平上已经证明，人、哺乳动物和某些鸟类中都有IL-18存在。
Interleukin-18 (IL-18) is a pro-inflammatory factor, and adipose tissue is one of its important sources.
白细胞介素18 (IL - 18)是一种前炎性因子，脂肪组织为其重要来源之一。
Objective to investigate the changes of interleukin 18 (IL-18) levels in serum in patients with systemic lupus erythematosus (SLE) and its relationship with the activity of SLE.
目的探讨白细胞介素18 (IL - 18)在系统性红斑狼疮(SLE)患者血清中的水平变化及其与SLE活动性的关系。
A weak anion exchange column was prepared and a separation method of interleukin-18 (IL-18) was developed on the column.
制备了弱阴离子交换整体柱，并建立了白介素18在该柱上分离纯化的方法。
The proliferative response of T-lymphocyte to exogenous IL-2 was studied in 18 maintenance hemodialysis (MHD) patients.
报告18例维持性血液透析(MHD)患者T淋巴细胞对外源性白细胞介素- 2 (IL - 2)的增殖反应。
Recently, elevated IL-18 levels were found in serum from some leukemia patients, especially those with acute lymphocytic leukemia (all) and chronic myeloid leukemia (CML).
近来，研究发现急性淋巴细胞白血病(all)和慢性粒细胞白血病(CML)患者血清中il - 18水平高于正常人。
Objective To explore potential synergetic effects of interleukin-2 (IL-2) with IL-18 on induction of natural killer (NK) cell activity against myeloma cells in vitro.
目的研究白细胞介素- 2 (IL - 2)和白细胞介素- 18 (IL - 18)诱导自然杀伤(NK)细胞活化和抗骨髓瘤细胞活性的协同作用。
Objective: to investigate whether high mobility group box chromosomal protein 1 (HMGB1) can activate macrophages to secrete IL-18.
目的：探讨高迁移率族蛋白1 (HMGB1)能否激活巨噬细胞表达IL - 18及其受体。
To study rudimentarily the role of IL-18 in acute immunity hepatic injury, and the important of blocking cascade reaction of cytokines by exerting IL-18 antibody in early stage.
通过动物实验，初步探讨IL-18在急性免疫性肝损伤中的意义，及早期使用IL-18抗体及时阻断细胞因子级联反应对保护肝组织的重要性。
CONCLUSION the level of IL-18 increases obviously on the 1st day of ACI onset and gradually decreases with the extended course of disease and time of treatment.
结论：白细胞介素18水平在发生急性脑梗死第1天时明显升高，随发病和治疗时间的延长，其水平逐渐下降。
Objective To detect the clinical significance of changes of serum cyclooxygenase-2 (COX-2) activity and interleukin-18 (IL-18) in patients with T2DM diagnosed by the first time.
目的探讨初发2型糖尿病患者外周血中环氧化酶2（COX-2）活性与白介素18（IL-18）含量变化的临床意义。
Conclusion: the immune status is low in gastric cancer tissue and it can be conjectured that this phenomenon relates to the deficiency of 4-1bbl and IL-18.
结论：胃癌组织内处于低免疫状态，推测肿瘤细胞免疫逃逸现象可能与4 - 1bbl和IL - 18的缺乏有关。
To explore the effects of IL-18 gene transfection on the proliferation of C6 glioma cell.
探讨IL-18基因转染对大鼠C6胶质瘤细胞生长特性的影响。
Conclusion: IL-18 in combination with IL-2 may increase the anti-tumor activity of NK92, which provides the experimental basis for immunotherapy of ovarian tumor with NK92 cells.
结论：IL - 18联合IL - 2可提高NK92细胞的抗肿瘤活性，为临床应用NK92细胞免疫治疗卵巢肿瘤提供了实验依据。
Through the analysis of the software, it could be found that the secondary structure of IL-18 mature peptide has almost unchanged after fusion and remain its bioactivity.
其相应的氨基酸序列经软件分析，并与人il - 18的成熟肽单独的分析结果相比较，发现在二级结构水平几乎没有变化，融合过程未影响IL - 18的活性。
The purpose of the study was to evaluate the serum concentration and mRNA expression of IL - 13 and IL - 18 before and after the methylprednisolone pulse therapy ( MPT) in PNS.
本实验通过观察白细胞介素13（IL-13）及白细胞介素18（IL-18）在小儿PNS中的变化探讨其在PNS发病中的变化及甲基强的松龙冲击治疗（MPT）对IL-13及IL-18表达的影响。
Methods An enzyme-linked immunosorbent assay(ELISA)was utilized to detect the levels of IL-18, VEGF in serum of 75 patients with HSP.
方法采用固相酶联免疫分析法检测75例过敏性紫癜患者血清IL-18、VEGF水平。
Conclusion: the IL-18 is high in PAR patients and the persistence of elevated IL-18 concentration suggests its role in the expression of persistence and exacerbation of allergic inflammation.
结论：变应性鼻炎患者血清il 18表达增高，在变应性炎症的持续存在和恶化过程中起重要作用。
Results: The D-Gal-treated rats significantly experienced a dynamic escalation of ALT, AST and IL-18 levels(P<0.05).
结果：D-氨基半乳糖造模后，两组大鼠血清ALT，AST和肝匀浆IL-18值呈动态升高（P<0.05）。
Objective To measure the serum level of interleukin-18(IL-18) in patients with chronic myelocytic leukemia (CML).
目的：检测慢性粒细胞白血病（CML）患者血清IL-18水平。
Therefore, IL-18 should be seen as a unique molecule that constitutes a critical link between innate and adaptive immunity.
因此，IL - 18为联系机体天然免疫和获得性免疫的关键活性分子。
Background: Interleukin (IL) -18 is a proinflammatory cytokine and plays important regulating roles in various immune reactions.
背景：白细胞介素(IL)鄄18是一种促炎性细胞因子，对多种免疫反应具有重要调节作用。
Results: IL-12 and IL-18 induced prominent spleen deficiency syndrome similar with that induced by reserpine.
结果：IL - 12及IL - 18引起明显脾虚证的表现，与利血平制作脾虚动物模型组相似。
Methods The plasma IL-18 in 36 ITP patients and 36 normal controls were detected by enzyme linked immunosorbent assay (ELISA).
方法酶联免疫吸附测定(ELISA)测定血浆IL - 18，对36例itp患者和正常对照组血浆IL - 18的水平进行分析。
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