Integrin is often significantly up-regulated in activated endothelial cells during tumor angiogenesis.
在肿瘤血管生成过程中,活化血管内皮细胞整合素表达明显上调。
The infection efficiency of adenovirus is determined by the levels of CAR and integrin on cancer cells.
肿瘤细胞表面CAR和整合素的表达水平决定了腺病毒对肿瘤细胞的感染效率。
Conclusion: the infection efficiency of adenovirus is determined by the levels of CAR and integrin on cancer cells.
结论:肿瘤细胞表面CAR和整合素的表达水平决定了腺病毒对肿瘤细胞的感染效率。
Objective Investigation of the effect of integrin on fibroblasts from scleroderma in the production of procollagen.
目的研究硬皮病成纤维细胞整合素表达对成纤维细胞合成原胶原的影响。
Integrin played important roles in development of Drosophlia and innate immune response of some lepidoptera insects.
在昆虫中整合素对果蝇的生长发育及一些鳞翅目昆虫的先天性免疫反应起重要作用。
This article reviews and gives summary of current research on integrin and the metastasis of ovarian cancer invasion.
本文将就整合素和卵巢癌侵袭转移研究现状进行综述。
Osteopontin(OPN) is an integrin-binding protein, believed to be involved in a variety of physiological cellular functions.
骨桥蛋白(OPN)是分泌性细胞的细胞外基质蛋白,与细胞的多种生理功能关系密切。
Objective to investigate the effects of photochemotherapy on the angiogenic ability of endothelial cells and expression of integrin.
目的探讨光化学疗法对内皮细胞管腔形成能力及整合素表达的影响。
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as integrin receptor antagonists.
本发明涉及化合物及其衍生物、它们的合成方法以及它们作为整联蛋白受体拮抗剂的用途。
And the mechanism of the signal transduction among integrin, cytoskeletons and FAK in the invasion and metastasis of CRC were explored.
探讨了整合素、细胞骨架、FAK在大肠癌侵袭转移中的信号转导机制。
Integrin is an important receptor of cellular adhesion molecules, which mediates the adhesion between cell and cell or cell and extracellular matrix.
整合素是一类介导细胞与细胞外基质及细胞与细胞间黏附的细胞黏附分子受体。
Conclusion Overproduction of procollagen may be inhibited in the level of transcription by lowering the expression of integrin on fibroblasts in scleroderma.
结论降低硬皮病成纤维细胞整合素的表达,可从转录水平抑制成纤维细胞合成原胶原。
Blocking integrin-mediated leukocyte adhesion, although beneficial in experimental models, has had limited success in treating inflammatory diseases in humans.
阻断整合素介导的白细胞黏附(尽管在实验模型中是有裨益的)在治疗人类的炎症性疾病上所获得的成功是有限的。
AIM: To explore the effect of simvastatin on expression of integrin-linked kinase (ILK) and the injury of renal tubulointerstitium in the rats induced by high fat diet.
目的:探讨辛伐他汀对高脂诱导的大鼠肾组织整合素连接激酶(ILK)的表达及其对肾小管间质损害的影响。
Lymphocyte function associated antigen-1 (LFA-1) is a member of integrin family, that plays an important role in the adhesion of lymphocytes with other cells and matrix.
淋巴细胞功能相关抗原(LFA-1)属于黏附分子家族,在细胞相互作用中发挥重要作用。
The invention relates to a cyclopeptide analog and a cyclization method thereof, which aims at providing an integrin ligand cyclopeptide analog and a cyclization method thereof.
本发明涉及环肽类似物及其环化方法,旨在提供一种整合素配体环肽类似物及其环化方法。
Integrin, a kind of adhesion molecule generally exists on the cell surface, mediates adhesion and information transmissions between cell-cell and between cell-extracellular matrix.
整合素是一类广泛存在于细胞表面的粘附分子,介导细胞—细胞及细胞—细胞外基质间的粘附及信息传导。
We were therefore interested in determining whether OPN could functionally contribute to lymphatic metastasis and also whether the RGD integrin-binding region was important for this process.
因此,我们对于OPN是否在淋巴转移中起功能性作用以及RGD序列在此过程中的重要性非常关注。
Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, suppressing expression of integrin expression in cultured glomerular epithelial cells.
氨基核苷嘌呤霉素诱导肾病变是人原发性肾病综合症的模型,抑制培养的肾小球上皮细胞整联蛋白的表达。
"The cell signal factor SCAI controls the formation and function of b1-integrin," says Dr. Robert Grosse. "If there is too little SCAI in tumor cells, then b1-integrin is overactive, so to speak."
RobertGrosse博士说:“细胞信号因子scai控制b1 -整联蛋白的形成和功能,可以说,如果肿瘤细胞中scai太少,b1 -整联蛋白就会表现得过度活跃。”
"The cell signal factor SCAI controls the formation and function of b1-integrin," says Dr. Robert Grosse. "If there is too little SCAI in tumor cells, then b1-integrin is overactive, so to speak."
RobertGrosse博士说:“细胞信号因子scai控制b1 -整联蛋白的形成和功能,可以说,如果肿瘤细胞中scai太少,b1 -整联蛋白就会表现得过度活跃。”
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