Objective To investigate the hepatic safety of itraconazole intravenous solution in the treatment of invasive fungal infection.
目的评估伊曲康唑注射液治疗侵袭性真菌感染的肝脏安全性。
Invasive fungal infection (ifi) is associated with significant morbidity and mortality in patients with hematologic malignancies.
侵袭性真菌感染(ifi)是导致恶性血液病患者发病和死亡的重要原因之一。
Objective:To investigate the effects of voriconazole in patients with malignant hematological disorders complicated by invasive fungal infection.
目的：探讨伏立康唑治疗恶性血液病患者合并侵袭性真菌感染的结果。
Objective To understand the risk of invasive fungal infection at phase of preengraft- ment of allogeneic hematopoietic stem cell transplantation(HSCT).
目的提高对异基因造血干细胞移植后早期深部真菌感染风险的认识。
Results the incidence of invasive fungal infection is 13.8%, elderly patients, higer WBC counts and longer antibiotics treatment are the risk factor for the fungal infection.
结果急性白血病诱导化疗期间真菌感染发生率为13.8%。发生真菌感染的危险因素有老年、高白细胞以及使用广谱抗生素时间较长。
Recently, there have been several significant changes in IDSA guidelines especially in the treatment of invasive fungal infection because of developments in several antifungal agents.
近来，由于多种抗真菌药物的问世，IDSA的指南出现了一些显著变化，尤其是针对侵袭性真菌感染的治疗。
Invasive fungal infection (IFI) is an important cause of morbidity and mortality in patients with hematologic malignancy, prolonged neutropenia, or after hematopoietic stem cell transplant.
侵袭性真菌感染(ifi)是恶性血液病、长时间中性粒细胞减少或造血干细胞移植后患者重要的发病和死亡原因之一。
Infection with either can lead to severe life-threatening disease, particularly in immunosuppressed patients, with mortality rates for invasive fungal disease often exceeding 30%.
这两种感染都是严重威胁生命的疾病，尤其对于免疫功能抑制的患者，侵袭性真菌疾病所致的死亡率常超过30%。
The factors related to nosocomial fungal infection were the severity of the primary disease, long-term use of antibiotics and glucocorticoid, invasive procedure.
病情危重，长期应用抗生素、激素及侵袭性操作均是真菌感染的因素。
The factors related to nosocomial fungal infection were the severity of the primary disease, long-term use of antibiotics and glucocorticoid, invasive procedure.
病情危重，长期应用抗生素、激素及侵袭性操作均是真菌感染的因素。
应用推荐