Establish a method for the determination of quinapril and its active metabolite quinaprilat in human plasma.
建立一种方法测定人血浆中喹那普利及其代谢产物喹那普利拉的浓度。
Cigarette smoking induces CYP1A2 and may, therefore, enhance the conversion of clopidogrel to its active metabolite.
吸烟诱导CYP1A2而且可能因此增强氯吡格雷转化为其活性代谢产物。
Objective: To establish an HPLC method to determine the plasma concentrations of buspirone hydro-chloride (BuHCl) and its active metabolite 1 - pyrimidinyl - piperazine(1 - PP).
目的:建立高效液相色谱法测定血浆中盐酸丁螺环酮及其活性代谢物1-嘧啶哌嗪浓度的方法。
Objective:To establish a SPE-HPLC method for the determination of quinapril and its active metabolite quinaprilat in human plasma and to evaluate their pharmacokinetics and relative bioavailability.
目的:建立SPE—HPLC法测定人血浆中喹那普利及其代谢产物喹那普利拉的浓度,以研究喹那普利及喹那普利拉在健康志愿者中的药代动力学和相对生物利用度。
The new type of antihistamine, fexofenadine, an active metabolite of tefanadine, was introduced with its pharmacology and clinical application.
介绍了新型抗组胺药非索非那定的药理作用及临床应用。
The new type of antihistamine, fexofenadine, an active metabolite of tefanadine, was introduced with its pharmacology and clinical application.
介绍了新型抗组胺药非索非那定的药理作用及临床应用。
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