• The defective mismatch repair system may result in mutations of genome and cause tumors.

    错配修复系统缺陷可能导致遗传物质发生突变引发恶性肿瘤

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  • But the large loop repair, a distinct repair from mismatch repair, is an unknown repair system.

    但是大型核酸环修复一个迥异配对错误的修复机制却是未知的系统。

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  • This paper reviewed the relationship between DNA mismatch repair, chromosome instability and cancer.

    本文DNA错配修复染色体不稳定肿瘤之间联系予以综述

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  • In several but not all cases, mutators have been found to contain defects in mismatch repair (MMR) pathways;

    一些不是所有情况下存取器发现含有缺陷错配修复MMR途径

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  • When function defects of mismatch repair genes, Cell Showes Genomic instability because of the aggregation of mutation.

    错配修复基因功能缺失细胞常会基因突变聚集而表现遗传不稳定

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  • DNA mismatch repair system could recognize and repair mistakes in process of DNA replication, guard stability and integrality of genome.

    DNA错配修复系统可以识别纠正DNA复制过程出现错误保证基因组稳定性完整性

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  • The overwhelming majority of traditional serrated adenomas retain mismatch repair enzyme function indicating a microsatellite-stable phenotype.

    绝大多数传统锯齿状腺瘤保留错配修复功能表明卫星稳定表型。

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  • Background Surgical management of colon cancer for patients with Lynch syndrome who carry a mismatch repair (MMR) gene mutation is controversial.

    背景那些携带错配修复(MMR)基因突变林奇综合症直肠癌患者来说,手术方式有争议的。

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  • Consequence of homologous recombination, in which hybridization between different alleles causes one allele to be converted into the other. This occurs by mismatch repair.

    同源重组后果不同等位基因之间杂交使其中的等位基因转换成了一个等位基因。错配修复引起的。

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  • In gastrointestinal adenocarcinomas, PD-L1-expression was associated with EBER positivity and mismatch-repair deficiency.

    胃肠道癌中,PD-L1表达EBER阳性错配修复缺陷相关。

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  • In gastrointestinal adenocarcinomas, PD-L1-expression was associated with EBER positivity and mismatch-repair deficiency.

    胃肠道癌中,PD-L1表达EBER阳性错配修复缺陷相关。

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