Objective To establish an appropriate model of focal ischemiareperfusion in experimental chronic diabetic rats and comparatively analyze the factors influencing successful preparation of model.
目的建立合适的实验性慢性糖尿病大鼠局灶性脑缺血再灌注模型,并比较分析影响模型制备成功的因素。
RESULTS: a total of 24 rats in the control group, 24 rats in the diabetic model group and 5 rats in the diabetic nephropathy group were involved in the result analysis.
结果:对照组大鼠24只,糖尿病模型组大鼠24只,糖尿病肾病待定组大鼠5只全部进入结果分析。
Methods Diabetic model of rats was induced by streptozotocin.
方法以链脲佐菌素造成大鼠糖尿病模型。
METHODS The diabetic model of SD rats was induced by STZ, and the activity of GSH-PX and the content of MDA of liver tissue were measured in per groups.
采用链脲佐菌素诱导制作糖尿病大鼠模型,分别测定各组大鼠肝组织中GSH-PX活性及MDA含量。
Objective:To observe the effects of Gushen capsule on lipidic metabolism and oxygen derived free radidicals in rats model of diabetic nephropathy(DN).
目的:观察固肾胶囊对糖尿病肾病(DN)大鼠脂质代谢及氧自由基的影响。
RESULTS After fed with sodium orthovanadate, the plasma glucose levels of the type 2 diabetic rats were obviously lower than those of the diabetes model rats(P<0.05).
结果①2型糖尿病大鼠经原钒酸钠灌胃给药后,空腹血糖值与模型组相比有明显的降低(P<0.05);
METHODS: The model of type 2 diabetic rats with hyperlipemia was established by injecting low dosage of streptozotocin (STZ) and feeding with high fat diet.
方法:采用低剂量链脲佐菌素尾静脉注射联合高脂饲料喂养建立2型糖尿病合并高脂血症大鼠模型。
METHODS: The model of type 2 diabetic rats with hyperlipemia was established by injecting low dosage of streptozotocin (STZ) and feeding with high fat diet.
方法:采用低剂量链脲佐菌素尾静脉注射联合高脂饲料喂养建立2型糖尿病合并高脂血症大鼠模型。
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