Neuropathic pain is driven by nerves gone wrong.
神经疼痛是由神经紊乱造成的。
The mechanisms of peripheral neuropathic pain are rather complex.
周围神经病理性疼痛的机制较复杂。
Neuropathic pain is a familiar sight of many patients and it can be suffering.
神经损伤所致病理性痛是临床上常见的病理性痛之一，它给患者带来极大的痛苦。
This review summaries the pathophysiology and treatment of chronic neuropathic pain.
本文就其治疗的进展及机制作一综述。
Neuropathic pain has long been described as the result of dysfunctional neuronal changes.
传统观念认为神经病理性疼痛主要是由神经元的功能改变所引起的。
This is the first evidence of a genetic contribution to the risk of developing neuropathic pain in humans.
这项试验首次证实了基因因素参与了人类患上神经源性疼痛的风险。
Consider treatment with duloxetine, pregabalin, and gabapentin to improve quality of life in patients with neuropathic pain.
C考虑使用度洛西汀、普瑞巴林和加巴喷丁治疗以改善神经性疼痛患者的生活质量。
No significant correlation was found between or among the presence of spasticity, neuropathic pain, and ASIA score at final visit.
在痉挛、神经性疼痛和最终的ASIA评分之间无明显相关性。
Gabapentin, which has been used in the treatment of neuropathic pain, may be effective in the treatment of symptoms associated with LSS.
加巴喷丁对神经性疼痛疗效确切，因此可能对腰椎管狭窄症症状缓解有效。
Objective: To investigate the influence of propofol on the activation of astrocytes in the spinal cord of rats with chronic neuropathic pain.
目的：研究丙泊酚对慢性神经痛大鼠脊髓星形胶质细胞激活的影响。
But except for some rare inherited conditions, there has been no evidence that genetics contributed to the risk of neuropathic pain in humans.
但是除了一些遗传情况，没有其他证据说明基因因素参与了人类患神经源性疼痛的风险度。
The behavior results showed that blocking peripheral 5-HT_(2A)receptors inhibited the thermal hyperalgesia in inflammatory and neuropathic pain.
行为学结果显示，阻断外周5-HT_（2A）受体能够明显抑制慢性炎症及神经病理性痛引发的热痛觉过敏。
Further, the mutant mice proved more sensitive than normal mice to inflammatory pain and neuropathic pain, two common forms of chronic pain in humans.
此外，证明突变小鼠比正常小鼠在人类常见的两种疼痛即炎症性疼痛和神经性疼痛方面更敏感。
Objective: To investigate the relationship between the spinal astrocytic activation and neuropathic pain behavior in L5 spinal nerve ligation (SNL) rats.
目的：研究L5脊神经结扎模型大鼠脊髓星形胶质细胞的激活与痛行为之间的关系。
Neuropathic pain is an intractable chronic pain. The efficacy of sodium channel inhibitor for treating these pain has been researched during the past decade.
神经病理性疼痛是慢性疼痛中的研究热点，其产生机制复杂，治疗方法虽多，但尚未有适用于各种类型神经病理性疼痛的疗法。
The wounds are completely closed, he still complains about some neuropathic pain but that is normal for that kind of damage that he had in his nerves and so on.
伤口已经完全闭合，他还有神经痛，但对于这种伤了神经的伤害来讲是正常的。
Methods: Using L5 spinal nerve ligation as neuropathic pain model of rats, teased fiber recording technique was used to explore the property of ectopic discharges.
方法：以L 5脊神经结扎制备大鼠神经病理性痛模型，利用分离背根单纤维细胞外电生理记录异位放电。
By measuring the speed the mice withdrew from different types of painful stimuli, the scientists were able to show that deleting the HCN2 gene took away neuropathic pain.
通过记录小白鼠回避不同类型疼痛的速度，科学家们终于可以断言，移除HCN2基因可使其感受不到神经性疼痛。
Ibudilast, an inhibitor of glial activation and cyclic nucleotide phosphodiesterases, has shown potential in the treatment of neuropathic pain and opioid withdrawal.
异丁司特作为一种神经胶质激活和环核苷酸磷酸二酯酶抑制剂，已被显示有治疗神经性疼痛和阿片脱瘾的可能性。
These findings support the hypothesis that peripheral buccal nerve compression could be an etiology of paroxysmal neuropathic pain in the unilateral orofacial region.
这些发现支持这一假设周围颊神经压迫可能是神经性疼痛阵发性在颌面部地区的单边病因。
The present study aimed to explore the effects of 5-HT1A receptors in the distal cerebral spinal fluid-contacting neurons (CSF-CNs) in rat brain parenchyma in neuropathic pain.
本文旨在探讨大鼠脑实质内远位触液神经元中5-HT1A受体的分布及其在神经病理性痛中的作用。
The pain behaviour expressed by dogs with syringomyelia suggests that they experience neuropathic pain, probably due to disordered neural processing in the damaged dorsal horn.
患有脊髓空洞症的犬类对疼痛动作的表达表明它们曾有神经性疼痛症状，可能是患损害脊髓后角的神经性疾病。
Three case reports in this article illustrate the diagnostic methods used and the treatment course encountered for many patients with diabetic peripheral neuropathic pain (DPNP).
三个病例报告说明本文中所使用的诊断方法和治疗过程中遇到的许多患者糖尿病周围神经性疼痛(dpnp)。
Neuropathic pain is a chronic condition affecting millions of people worldwide, and current treatments are often inadequate, ineffective or associated with potential severe side effects.
疼痛做为一种慢性疾病，威胁着全球数百万患者，而目前的治疗方法效果欠佳且副作用较多。
Facial treatment of neuropathic pain which best hospital, in what place? Pain is a kind of complex mental state, psychological and physiological and behavioral reactions produce certain effect.
山东治疗面部神经痛的医院哪家最好，在什么地方呢？推荐商户复大面神经康复治疗中心。
Conclusion: Transplanting xenogenetic chromaffin cells into subarachnoid space can reduce neuropathic pain effectively, and this antinociception is conducted via adrenoreceptors and opiate receptors.
结论：蛛网膜下腔移植嗜铬细胞能有效缓解神经性疼痛，并能增强宿主对外源性阿片制剂的敏感性。
Thus, P2X4 receptors and the intracellular signaling mediators in microglia are promising therapeutic targets for the development of novel pharmacological agents in the management of neuropathic pain.
因此，P 2x4受体和细胞内信号传导介质中的小胶质细胞是有希望的治疗靶点，为开发新的药物在神经性疼痛的管理。
Thus, P2X4 receptors and the intracellular signaling mediators in microglia are promising therapeutic targets for the development of novel pharmacological agents in the management of neuropathic pain.
因此，P 2x4受体和细胞内信号传导介质中的小胶质细胞是有希望的治疗靶点，为开发新的药物在神经性疼痛的管理。
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