The chiral HMPA analogues were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.
通过磷酰氯与手性仲胺的亲核取代反应高产率地合成了手性HMPA 类似物。
The first is extremely resistant to nucleophilic reagents.
前者极端地阻抗亲核试剂。
A stepwise nucleophilic displacement involving 36 was highly unlikely.
涉及36的这种逐步亲核取代是不大可能的。
The nucleophilic ability of the amines had effect on the yields of the amides as well.
胺的亲核能力对酰胺的收率也有一定的影响。
Kinetics of the Nucleophilic Substitution of 3-amino-1, 2, 4-triazole with Picryl Chloride.
氨基- 1,2,4 -三唑与苦基氯的亲核取代反应动力学研究。
Nucleophilic Aromatic Substitution. Strategies in the Synthesis of Multisubstituted Benzene Derivatives.
亲核性芳香取代。多取代苯衍生物合成的策略。
According to the experimental results, it was assumed that the cyclization was taken by nucleophilic attack.
根据实验结果，我们推测反应的关键步骤为亲核进攻。
Quaternarization is an important SN2 nucleophilic substitution reaction; solvent has remarkable effect on it.
季铵化反应是一类重要的SN2亲核取代反应，溶剂对该反应的影响很显著。
To study the nucleophilic addition of N-methylhydroxylamine and O-methylhydroxylamine to unsaturated nitro compounds.
研究N-甲基羟胺与O-甲基羟胺对不饱和硝基化合物的加成反应。
Michael reaction is a typical nucleophilic addition reaction, is always an organic chemistry domain research hot spot.
迈克尔反应是一个典型的亲核加成反应，一直是有机化学领域的一个研究热点。
METHODS: Electrophilic substitution, reduction, oxidation and nucleophilic addition reaction were used in the synthesis of title compounds.
方法：通过亲核取代、还原、氧化、亲核加成等反应得到目的化合物。
There are impact factor to be discussed such as solvent polarity, nucleofuge, attract electron group the nunucleophilicity of nucleophilic reagent.
探讨碱性、溶剂极性、离去基团、吸电子基团、亲核试剂的亲核性对反应影响。
The mechanism of Hofmann rearrangement reaction and the effects of alkyl structure and nucleophilic reagent in medium on the reaction are discussed.
讨论了Hofmann重排反应的机理以及烃基的结构、介质中的亲核试剂对反应的影响，并介绍了此重排在有机合成中的应用。
The chiral HMPA analogues 1 and 2 were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.
以磷酰氯为原料通过与手性仲胺的亲核取代反应高产率地合成了手性HMPA类似物。
Moclobelide was synthesized from ethanolamine by nucleophilic substitution and Schotten-Baumann reaction, followed by condensation with an overall yield of 71.2%.
以乙醇胺为起始原料，经亲核取代、肖特一鲍曼反应和缩合反应制得吗氯贝胺，总收率可达71.2%。
The effect of process conditions, such as microwave, reactant ratio, catalyst and solvent etc, on the nucleophilic substitution and yield of product were investigated.
考察了微波技术、反应物料比、催化剂以及溶剂等主要条件对亲核取代反应和产物收率的影响。
Some novel copolyethers containing azo benzene chromophors as side chains have been synthesized by a nucleophilic reaction of various azo dyes with polyepichlorohydrin.
研究了由对硝基苯基偶氮苯类染料与聚环氧氯丙烷经大分子反应合成的含偶氮苯侧基的共聚醚的二阶非线性光学特性。
Aripiprazole in overall yield of 68% was synthesized from 2, 3-dichloroaniline by a three-step nucleophilic substitution reaction in yield of 83%, 91% and 90%, respectively.
以2,3 -二氯苯胺为原料，经3步亲核取代反应合成了阿立哌唑。3步反应的收率分别为83%，91%和90%；总收率68%。
Five derivative dyes from the parent dyes were obtained by similar nucleophilic substitution reaction in which five primary amines were employed as the nucleophilic reagent.
将母体染料的中位氯原子用氨基试剂亲核取代，衍生合成了五个中位仲胺七甲川菁染料。
Vicarious nucleophilic substitution (VNS) of hydrogen is a new type of reaction which is different from the usual electrophilic and nucleophilic reactions of the nitro arenes.
氢的替代亲核取代反应(VNS)是与硝基芳环的亲电反应、亲核反应不同的一种新反应。
Trapping reactions in singlet oxygenation of 2-phenylindole (1) and nucleophilic addition reactions of 2-phenyl-3H-indol-3-one (4) both in methanolic media were studied comparatively.
本文比较了在甲醇介质下，2-苯基吲哚（1）单重态氧反应中的捕捉反应以及2-苯基-3H-吲哚-3-酮（4）的亲核加成反应特征。
After it was mixed with epoxy resin, transition state was formed first. Then they got on with opening ring reactions according to bimolecular nucleophilic substitution mechanism (SN2).
它与环氧树脂混合后首先形成过渡状态，然后按双分子亲核取代(SN2)机理进行开环反应。
Methods:Starting from 5-cyanophthalide, escitalopram oxalate was prepared via several steps including nucleophilic addition, hydrolysis, chemical separation, cyclization and salt formation.
方法：以5-氰基苯酞为起始原料，经亲核加成、水解、化学拆分、环化和成盐等反应制得抗抑郁药草酸依地普仑。
At the same time, discuss about the impact factor to nucleophilicity such as the number of attract electron group, ability of attract electron and the nucleophilic substitution reaction part.
并且对亲核试剂的体积效应、溶剂效应对亲核性影响，底物上吸电子基团的数目、吸电子能力对亲电性的影响，以及亲核取代反应的发生部位受哪些因素影响进行探讨。
The key step of the two routes is the reaction of nucleophilic substitution of aromatic amines and -bromo compounds. Generally the produce rate of this reaction is low and the reaction time is long.
两条路线中关键的一步反应是芳胺和溴代化合物的亲核取代反应，一般这步反应产率很低，并且需要较长的反应时间。
Abstract : this article reviews recent progress in nucleophilic reactions of the - carbon in vinylidene ruthenium complexes. the nucleophiles include alkene, alkyne, alcohol, acid, amine, water, etc.
文摘：综述了近几年钌亚乙烯基络合物中间体-碳的亲核反应。亲核试剂包括烯烃、炔烃、醇、酸、胺、水等。
Abstract : this article reviews recent progress in nucleophilic reactions of the - carbon in vinylidene ruthenium complexes. the nucleophiles include alkene, alkyne, alcohol, acid, amine, water, etc.
文摘：综述了近几年钌亚乙烯基络合物中间体-碳的亲核反应。亲核试剂包括烯烃、炔烃、醇、酸、胺、水等。
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