2,5- and 2,6-disubstituted benzazole analogues are used as protein kinase inhibitors.
2,5和2,6双取代氮茚类似物被用作蛋白激酶抑制剂。
Cyclic AMP binds to the regulatory subunit of protein kinase A: Protein kinase A phosphorylates phosphorylase kinase.
环腺苷酸结合蛋白激酶的调节亚基:一个磷酸化蛋白激酶磷酸化酶激酶。
The latter encodes a novel protein kinase with LIM domains and is strongly expressed in the brain.
后者以LIM范围编码了一个新奇的蛋白质激酶,并且在大脑中强烈地表达。
Products of viral oncogenes, most commonly retroviral oncogenes. They usually have transforming and often protein kinase activities.
病毒癌基因最常为逆转录病毒致癌基因的产物。通常具有转化和蛋白激酶活性。
Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.
在小鼠模型中,GNA11突变诱导了自发转移性肿瘤,激活了丝裂原活化蛋白激酶途径。
It binds and activates protein kinase c, causing a wide range of effects in cells and tissues (1, 2).
它结合并激活蛋白激酶c,对很多细胞和组织产生影响(1,2)。
Receptor tyrosine protein kinase is one of key kinases in cell signal transduction and plays an important role in the process of cell growth, development and functions regulated by growth factors.
受体酪氨酸蛋白激酶是细胞信号转导进行的关键信号酶,在生长因子调控细胞生长、发育与功能的过程中起着重要的生理作用。
Objective:To search for natural substrates of protein kinase CK2 in pig platelets.
目的:寻找猪血小板中蛋白激酶CK2可能的天然底物。
AIM: to observe the inhibitory effect of luteolin on recombinant human protein kinase CK2 holoenzyme and to confirm the inhibitory type by its enzyme kinetic analysis in vitro.
目的:观察体外藤黄菌素对重组人蛋白激酶CK2的抑制效果及进行酶动力学分析以确定其抑制作用类型。
Objective: to study the influence of high cell incubating temperature on AMP-activated protein kinase (AMPK) activity and lipid metabolites of piglets hepatocytes in vitro.
目的:研究提高细胞培养温度对仔猪肝细胞一磷酸腺苷激活蛋白激酶(AMPK)活性及脂质代谢产物的影响。
It is systematically reviewed that the discovery of the plant protein kinase, including the research survey, family classification, the process of phosphorylation and the circadian function.
就近十年来国内外学者对植物蛋白激酶的发现,家族分类,磷酸化过程及其生理功能等方面的研究进行综述。
Objective: to investigate the expression of death associated protein kinase (DAPK) and the relationship between DAPK and cell apoptosis in breast carcinoma.
目的检测乳腺癌中死亡相关蛋白激酶(DAPK)表达,探讨其与细胞凋亡的关系及其在乳腺癌中的作用。
This gene, which encodes a protein kinase and is regulated by a small molecule called cyclic GMP, has been previously studied but not suspected to play a role in sleep regulation.
这个基因编码一种蛋白质激酶,并受环状GMP小分子的调节。该基因以前有过研究,但不知道它有一定的睡眠调节作用。
Xinshukang may decrease the high expression of myocardium protein kinase in rats with increasing pressure load and reverse the left ventricular hypertrophy.
心舒康可降低压力负荷增加大鼠心肌组织蛋白激酶的高表达,从而逆转其左心室肥厚。
Objective: To investigate the effects of AMP activated protein kinase (AMPK) activation on translocation of glucose transporter 4(GLUT4) and glucose uptake in hypoxic rat myocardium.
目的:探讨心肌缺氧时AMP激活的蛋白激酶(AMPK)激活对葡萄糖转运子4(GL UT4)移位和葡萄糖摄取的作用。
Objective To investigate the effects of blocking renin-angiotensin system on protein kinase C (PKC) activity in diabetic rat kidney.
目的观察阻断肾素血管紧张素系统对糖尿病大鼠肾组织蛋白激酶C(PKC)活性的影响。
Objective: To investigate the expression of extracellular signal regulated protein kinase(ERK) signal transduction pathway and its significance in the rat brain after epileptic seizures.
目的:研究细胞外信号调节蛋白激酶(ERK)信号通路在癫痫大鼠脑内的表达规律及其意义。
This study was to search specific CK2 inhibitors in tumor cells through observation of the inhibitory effects of baicalein on recombinant human protein kinase CK2 holoenzyme and its kinetics in vitro.
为了寻找肿瘤细胞内ck2的特异性抑制剂,本研究观察黄芩甙体外对重组人蛋白激酶CK2的抑制效果,并进行酶动力学分析以确定其抑制作用类型。
Many studies in recent years indicated that the activation and translocation of protein kinase C (PKC) of neurons in the dorsal horn of spinal cord was related with hyperalgesia.
但其详细机制并未完全阐明。近年来研究表明,脊髓后角神经元内蛋白激酶C(PKC)的激活和位移与痛感觉及痛过敏的形成有关。
Protein kinase C(PKC)activity of cell membrane was detected.
放射性同位素法检测肺癌细胞蛋白激酶C(PKC)活性。
Objective To study the effects of high glucose on activity of mitogen activated protein kinase (MAPK) in cultured human mesangial cells and to explain the mechanism of diabetic nephropathy.
目的:研究高糖对人肾小球系膜细胞丝裂原蛋白激酶(MAPK)活性的影响,探讨其在糖尿病肾病发病中的作用。
Objective To observe the changes in mitogen-activated protein kinase (MAPK)activity and gene expression after coronary artery balloon injury in rabbits.
目的探讨丝裂素活化蛋白激酶(MAPK)在动脉球囊损伤后内膜增殖过程中表达的变化。
Conclusion Genistein and daidzein were two effective inhibitors of recombinant human protein kinase CK2 in vitro.
结论染料木黄酮和大豆甙元是两种有效的重组人CK2全酶的抑制剂。
This study was to search specific CK2 inhibitors in tumor cells through observation of the inhibitory effects of baicalein on recombinant human protein kinase CK2 holoenzyme and its kinetic.
为了寻找肿瘤细胞内ck2的特异性抑制剂,本研究观察黄芩甙体外对重组人蛋白激酶CK2的抑制效果,并进行酶动力学分析以确定其抑制作用类型。
Objective To observed the influence of luteolin on protein kinase C activity in human leukemic cells (HL-60).
目的观察木犀草素对HL- 60细胞内蛋白激酶C活性的影响。
Objective to investigate the relationship between the expression of insulin receptor (ir) and the content of tyrosine protein kinase (TPK) in patients with hepatic cirrhosis.
目的探索肝硬化时肝组织细胞胰岛素受体(IR)和酪氨酸蛋白激酶(TPK)含量的变化规律。
The recombinant human protein kinase CK2 may be used as a molecular target for simpler screening and development of more effective inhibitors of CK2.
重组人蛋白激酶CK2可作为一种较为简便筛选和开发有效的CK 2抑制剂的分子靶点。
Objective to investigate the effect of mitogen-activated protein kinase (MAPK) on pathogenesis in myocardium hypertrophy of renal hypertension rats.
目的探讨丝裂素活化蛋白激酶(MAPK)在肾性高血压致心肌肥大中的作用。
Kinase Buffer can be used to assay protein kinase activity.
激酶缓冲液用来分析蛋白激酶的活性。
Kinase Buffer can be used to assay protein kinase activity.
激酶缓冲液用来分析蛋白激酶的活性。
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