JAK2 is a constitutive protein tyrosine kinase (PTK) which can activate JAK-STAT signaling.
JAK2是一种组成性酪氨酸激酶，能激活JAK - STAT信号传导途径。
Objective To approach the mechanism of action of anticancer and the investigation progress of protein tyrosine kinase (PTK).
目的探讨蛋白酪氨酸激酶抑制剂抗肿瘤作用机理及其研究进展。
Conclusions: the change of protein tyrosine kinase activity is involved in the differentiation of K562 cells induced by matrine.
结论：在苦参碱诱导K562细胞分化的过程中，涉及到蛋白酪氨酸激酶的活性改变。
In many inflammatory diseases such as septic shock (9), and psoriasis (10) the change in protein tyrosine kinase activity has been shown.
在许多炎症性疾病，如感染性休克(9)，与银屑病(10)，酪氨酸蛋白激酶的活动会表现出变化。
CONCLUSIONS AG1109 not only was an effective inhibitor of protein tyrosine kinases, but also was a novel potent inhibitor of protein kinase CK2.
结论：AG110 9不仅是酪氨酸蛋白激酶的抑制剂，而且是一种十分有效的蛋白激酶CK2的抑制剂。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂，能阻断酪氨酸蛋白激酶信号传导通路，从而促进肿瘤细胞凋亡。
Therefore, the aim of this study is to investigate the effects of genistein, a protein tyrosine kinase inhibitor, on acute and chronic inflammation in diabetic mice (induced by streptozotocin).
因此，本研究的目的是调查金雀异黄素，一种蛋白质酪氨酸激酶抑制剂，对有急性或慢性糖尿病炎症小鼠（诱导脲佐菌素）的影响。
Receptor tyrosine protein kinase is one of key kinases in cell signal transduction and plays an important role in the process of cell growth, development and functions regulated by growth factors.
受体酪氨酸蛋白激酶是细胞信号转导进行的关键信号酶，在生长因子调控细胞生长、发育与功能的过程中起着重要的生理作用。
Objective the study investigated the effect of gastrin on tyrosine phosphorylation and protein expression of focal adhesion kinase (FAK) in human colon cancer cells.
目的研究胃泌素对人结肠癌细胞信号分子黏着斑激酶(FAK)酪氨酸磷酸化和蛋白质表达的影响。
Objective to investigate the relationship between the expression of insulin receptor (ir) and the content of tyrosine protein kinase (TPK) in patients with hepatic cirrhosis.
目的探索肝硬化时肝组织细胞胰岛素受体(IR)和酪氨酸蛋白激酶(TPK)含量的变化规律。
Method The activity of tyrosine protein kinase(TPK) was determined by using exogenic substrates in 16 samples of normal skin, 22 psoriatic lesion and 5 skin squamous carcinoma.
方法通过外源性底物磷酸化方法，测定了16例正常皮肤、22 例银屑病皮损、5 例皮肤鳞癌组织角质形成细胞膜酪氨酸蛋白激酶（ T PK）的活性。
The tyrosine phosphorylated 130000 protein was identified as JAK2, a non receptor tyrosine kinase.
鉴定了分子量为130000酪氨酸磷酸化的蛋白质为JAK2，一种非受体型酪氨酸激酶。
In this paper, the tyrosine protein kinase activity of insulin receptor and its endogenous substrates were investigated on the human leukemia cell line K-562 differentiated by sodium butyrate.
本文对丁酸钠诱导分化的人白血病细胞株k- 562细胞的胰岛素受体酪氨酸蛋白激酶性及细胞内源性底物进行了研究。
JANEX-1 exhibits significant anti-leukemia activity, which could induce apoptosis in human lymphoblastic as well as myeloblastic leukemia cells with over-expressed tyrosine protein kinase.
JANEX- 1具有良好的抗白血病活性，它可诱导酪氨酸蛋白激酶过度表达的淋巴性白血病细胞和髓性白血病细胞凋亡。
JANEX-1 exhibits significant anti-leukemia activity, which could induce apoptosis in human lymphoblastic as well as myeloblastic leukemia cells with over-expressed tyrosine protein kinase.
JANEX- 1具有良好的抗白血病活性，它可诱导酪氨酸蛋白激酶过度表达的淋巴性白血病细胞和髓性白血病细胞凋亡。
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