Iron liberated from hemoglobin, and hemoglobin itself, are associated with the generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS).
血色素分解产生的铁离子和血红素本身与反应性氧自由基(ROS)和反应性氮自由基(RNS)的产生相关。
Reactive oxygen species can mediate signalling pathways in cardiac hypertrophy and cardiomyocyte apoptosis, and lead to endothelial dysfunction by inactivating nitrogen monoxide.
活性氧通过信号通路介导心肌细胞肥大和凋亡；通过灭活一氧化氮等机制导致内皮功能紊乱。
Reactive oxygen species can mediate signalling pathways in cardiac hypertrophy and cardiomyocyte apoptosis, and lead to endothelial dysfunction by inactivating nitrogen monoxide.
活性氧通过信号通路介导心肌细胞肥大和凋亡；通过灭活一氧化氮等机制导致内皮功能紊乱。
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