• Sunitinb is a novel multitargeted receptor tyrosine kinase inhibitor.

    苏尼替尼新型的多靶点酪氨酸激酶抑制剂

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  • The inhibitor of VEGF receptor tyrosine kinase was introduced in detail.

    详细介绍VEGF受体酪氨酸激酶抑制剂研究进展。

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  • The tyrosine phosphorylated 130000 protein was identified as JAK2, a non receptor tyrosine kinase.

    鉴定了分子量为130000酪氨酸磷酸化蛋白质JAK2一种受体型酪氨酸激酶

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  • HNMPA-AM3 -the insulin receptor tyrosine kinase inhibitor could block the anti-apoptosis effect of insulin.

    胰岛素受体自身酪氨酸磷酸化抑制剂一一HNMPA一AM3可以阻断胰岛素凋亡作用

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  • Objective: to establish a method of detecting insulin receptor tyrosine kinase (IRTK) activity from erythrocytes.

    目的建立红细胞胰岛素受体酪氨酸蛋白激酶(IRTK)的活性测定

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  • Objective:To explore the mutation of receptor tyrosine kinase ( RET ) gene in sporadic medullary thyroid carcinoma.

    目的研究散发甲状腺酪氨酸激酶受体基因RET突变情况。

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  • Objective to investigate the change of insulin receptor tyrosine kinase (TK) activity in the pathogenesis of insulin resistance (IR).

    目的探讨胰岛素受体酪氨酸激酶(TK)活性变化胰岛素抵抗(IR)发生中的作用。

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  • Gefitinib-sensitive mutations of the epidermal growth factor receptor tyrosine kinase domain in chinese patients with non-small cell lung cancer.

    中国细胞肺癌病人吉非替尼敏感的表皮生长因子受体酪氨酸激酶区域突变

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  • The phosphorylation assay proves that aldose reductase is the substrate of insulin-receptor tyrosine kinase and the Tyr(40) and Tyr(49) are phosphorylated by the kinase.

    试管内,未磷酸化还原磷酸化醛糖还原酶的动力学常数无差异,而细胞内的情况有待于进一步研究。

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  • Receptor tyrosine kinase-like orphan receptor-1 (ROR1) is expressed on sub-populations of B-cell malignancies and solid tumors, but not by healthy B cells or normal postpartum tissues.

    受体酪氨酸激酶样孤儿受体1(ROR1B-细胞恶性肿瘤实体亚群上表达的,不在健康B细胞正常产后组织中表达

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  • In this paper, the quantity of insulin receptors and the receptor tyrosine kinase activity and its endogenous substrates were comparatively studied in K-562 cells before and after transformation.

    对丁酸钠转化前后红白血病细胞k- 562的表面胰岛素受体数量、胰岛素受体酪氨酸蛋白激酶活性细胞内源性底物进行了研究

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  • Receptor tyrosine protein kinase is one of key kinases in cell signal transduction and plays an important role in the process of cell growth, development and functions regulated by growth factors.

    受体酪氨酸蛋白激酶细胞信号转导进行关键信号酶,生长因子调控细胞生长、发育功能过程中起重要生理作用

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  • Objective to investigate the relationship between the expression of insulin receptor (ir) and the content of tyrosine protein kinase (TPK) in patients with hepatic cirrhosis.

    目的探索肝硬化时组织细胞胰岛素受体(IR)酪氨酸蛋白激酶(TPK)含量变化规律。

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  • I suspect the way this worked when the first transmembrane receptors tyrosine kinase evolved was simply to make activation contingent on phosphorylation of one receptor by the other.

    第一个逐步变化的受体酪氨酸激酶通过受体被另外一个受体磷酸化而轻易实现临时激活时,怀疑这种作用方式

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  • Vascular epithelial growth factor binding with its receptor leads to cell proliferation and new vascular formation by tyrosine kinase pathway.

    血管内皮细胞生长因子与其受体结合后通过酪氨酸激酶途径引起细胞增殖新生血管形成

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  • Binding of FLT3L to its cognate tyrosine kinase receptor, FLT3, activates STAT3 and STAT5 (1, 3).

    FLT3L结合到与同源酪氨酸激酶受体FLT3结合激活STAT3STAT 5 (1,3)。

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  • PTK787 is the most promising VEGF receptor- tyrosine kinase inhibitor in pipeline because of its potency in tumor inhibition and oral bioavailability.

    PTK787肿瘤抑制出色疗效、口服生物利用度高等特点而成为VEGF受体酪氨酸激酶抑制剂中的佼佼者。

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  • Objective: to study Somatic mutation of the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR gene) in lung adenocarcinoma patients.

    目的探讨表皮生长因子受体(EGFR)基因酪氨酸激酶体细胞腺癌患者突变相关因素。

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  • In this paper, the tyrosine protein kinase activity of insulin receptor and its endogenous substrates were investigated on the human leukemia cell line K-562 differentiated by sodium butyrate.

    本文丁酸钠诱导分化白血病细胞株k- 562细胞胰岛素受体酪氨酸蛋白激酶细胞内源性底物进行了研究。

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  • In this paper, the tyrosine protein kinase activity of insulin receptor and its endogenous substrates were investigated on the human leukemia cell line K-562 differentiated by sodium butyrate.

    本文丁酸钠诱导分化白血病细胞株k- 562细胞胰岛素受体酪氨酸蛋白激酶细胞内源性底物进行了研究。

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