Renal fibrosis is the unifying feature of progressive renal alterations.
肾纤维化是肾脏改变的渐进统一的功能。
Extracellular matrix (ECM) accumulation is the final pathway to renal fibrosis.
细胞外基质(ecm)积聚是肾脏纤维化的最终途径。
Renal fibrosis is is the common pathway for a variety of chronic renal disease to final stage renal failure.
肾纤维化是各种慢性肾脏疾病进展到终末期肾衰竭的共同通路。
The relationships between expression of E2F-1 and degree of hydronephrosis and renal fibrosis were evaluated.
分析e2 F - 1表达与梗阻性肾积水和肾纤维化程度之间关系。
Objective To explore the curative effects of 1 (3 fluorophenyl) 5 methyl 2 (1H) pyridone (FMP) on renal fibrosis in rats.
目的：探讨1 （3氟苯基）5甲基2 （1H）吡啶酮对鼠肾纤维化的治疗作用。
Multiple causes can induce CKD but it is renal fibrosis that is commonly recognized as the single factor that leads to ESRD.
导致CKD发生原因可以多种多样，但进展至esrd的共同途径是肾脏纤维化。
Objective:To probe into the mechanism of Shenshuai Capsule in delaying advance of chronic renal failure(CRF)and against interstitial renal fibrosis.
目的：探讨肾衰胶囊延缓慢性肾功能衰竭（CRF）进展及抗肾间质纤维化的机理。
The proliferation of GMC can induce extracellular matrix(ECM) expansion, which can lead to glomerulosclerosis(GS), renal fibrosis and even end stage renal failure in the final.
GMC增殖可引起细胞外基质（ECM）过量生成和聚集，并最终导致肾小球硬化（GS）、肾脏纤维化及终末期肾功能衰竭。
ObjectiveTo study the role and significance of plasminogen activator inhibitor-1(PAI-1) in renal fibrosis(RF) after damage and elucidate the molecular pathogenetic mechanisms of RF.
为探讨纤溶酶原激活物抑制因子1（PAI 1）在肾损伤后纤维化中的作用和意义，揭示其发病的分子病理机制。
In Belgium, at least 70 people required renal transplants or dialysis for interstitial fibrosis of the kidney after taking the wrong herb from the Aristolochiaceae family, again as a dietary aid.
在比利时，至少有70个人在不正确地采用马兜铃科草药作为助食品而需要肾移植或因肾间质纤维化而做透析。
Objective To observe the protective effect of Biejiajian Pills on experimental rat kidney from renal interstitial fibrosis and discuss the mechanism.
目的观察鳖甲煎丸对肾间质纤维化实验大鼠肾脏的保护作用并探讨其作用机理。
OBJECTIVES: To determine the influence of hepatitis B virus (HBV) viral load and host-related factors on the progression of hepatic fibrosis in hepatitis B virus-infected renal transplant recipients.
目的：确定乙肝病毒载量的影响以及乙肝病毒感染的肾移植受者肝纤维化进程中宿主相关因素。
The imbalance of interstitial cell proliferation and apoptosis and the metabolic disorder of intercellular substance, are two essential factors for renal tubulointerstitial fibrosis.
间质细胞增殖和凋亡失衡及细胞间质代谢失调也是造成肾小管间质纤维化的两个不可缺少的原因。
Renal interstitial fibrosis; Renal tubular epithelial cell; Mitochondria oxidative damage; Renal tubular function.
肾间质纤维化；肾小管上皮细胞；线粒体氧化损伤；肾小管功能。
P21 may participate in the pathogenesis of renal tubule-interstitial fibrosis.
P21可能参与肾小管间质纤维化的发病过程。
Renal interstitial fibrosis is the common pathological procedure to renal function failure of many kinds of renal diseases.
肾间质纤维化是多种肾脏疾病走向肾功能衰竭的共同病理过程。
Conclusion Tetrandrine, tetramethylpyrazine and amygdalin may play important roles in prevention and reversion of renal interstitial fibrosis.
结论汉防己甲素、川芎嗪苦杏仁甙在预防及逆转肾间质纤维化中起重要作用。
Objective To study the protective effects of Shenyankangfu tablet on renal interstitial fibrosis in rats with unilateral ureteral obstruction (UUO).
目的：研究肾炎康复片对单侧输尿管梗阻(uuo)大鼠肾间质纤维化的保护作用。
Objective To investigate the expression of P21 in renal interstitial fibrosis rats and the effect of enalapril on it.
目的：动态观察P 21在单侧输尿管梗阻肾间质纤维化大鼠模型中的表达，以及依那普利对其表达的调节。
Results a progressive fibrosis was observed in renal stroma of the model.
结果模型显示肾间质呈进行性纤维化。
Objective: renal interstitial fibrosis is the common way to final renal failure. Renal interstitial fibrosis play more dangerous role than glomerulosclerosis in the kidney.
目的：肾间质纤维化是多种肾脏疾病进展至终末期肾衰竭的共同通路。
All the rats were sacrificed in 9 days, the kidneys were collected, and renal interstitial fibrosis was examined by PAS staining.
术后9天处死各组大鼠，肾组织标本用PAS染色确证肾间质纤维化病变。
The renal interstitial cells increased in rats of the model group with the basal membrane thickened and shrank as well as obvious fibrosis, which were aggravated with the time prolonging.
模型组大鼠肾小管间质细胞增多，肾小管基底膜增厚皱缩，纤维化明显，随时间进展而加重；
OBJECTIVE: the renal interstitial fibrosis (RIF) is almost the common pathway by which all the various chronic kidney diseases (CKD) progress to end stage renal disease (ESRD).
目的：肾间质纤维化(RIF)是各种不同病因的慢性肾脏病(CKD)随着病程进展进入终末期肾病(ESRD)的一个进行性、不可逆的共同途径。
Conclusions1. Mineralocorticoid inhibition can prevent chronic renal interstitial fibrosis caused by AA.
结论1、醛固酮抑制对AA所致的慢性肾间质纤维化有一定的防治作用。
Objective: To study the effects of "Kangxian Ling Decoction" (KLD) on renal interstitial fibrosis induced by unilateral ureteral obstruction (UUO) in rats.
目的：探讨中药抗纤灵方对大鼠单侧输尿管结扎(UUO)所致肾纤维化的防治作用及机制。
Connective tissue growth factor (CTGF) is generally considered has an important role in this pathological process, for the treatment of renal interstitial fibrosis research to provide new ideas.
现普遍认为结缔组织生长因子(CTGF)在此病理过程中有着相当重要的作用，将为研究治疗肾间质纤维化提供新的思路。
For example, ED5 reduces cortical Egr-1 mRNA expression and interstitial fibrosis in rats 7 days after renal obstruction (unilateral ureteral ligation) and delivery by electroporation.
例如，ED5可以减少小鼠尿路梗阻（单侧输尿管结扎）或通过电穿孔法切除肾脏7天后皮质早期生长反应基因-1信使RNA表达和间质纤维化。
The experiments on animal models are necessary for studying renal interstitial fibrosis. Researchers should find right animal models according to different objectives.
动物模型实验是研究肾间质纤维化必不可少的手段，实验者应根据不同的实验目的选择适当的动物模型。
Objective To explore whether the Astragalus injection (AI) has effect for reversing left ventricular hypertrophy and myocardial fibrosis induced by renal vascular hypertension in rats.
目的探讨黄芪注射液对肾血管性高血压大鼠左心室肥厚及心肌纤维化有无逆转作用。
应用推荐