Objective To investigate the relationship between RET proto oncogene and the pathogenesis of Hirschsprung′s disease.
目的探讨原癌基因RET与先天性巨结肠发生的关系。
Conclusion Mutation of RET proto oncogene might play an role in the familial Hirschsprung's disease.
结论RET基因突变与家族性先天性巨结肠症的发生有关。
Objective to investigate the relationship between the expression of RET proto oncogene and the pathogenesis of Hirschsprung's disease.
目的探讨RET基因的表达情况与先天性巨结肠发生的关系。
Method Exon 17 of RET proto oncogene from 30 children with Hirschsprung's disease was detected by PCR SSCP method.
方法应用PCRSSCP银染技术对30例先天性巨结肠原癌基因RET第17外显子进行检测。
Method Exon 17 of RET proto oncogene from 30 children with Hirschsprung's disease was detected by PCR SSCP method.
方法应用PCRSSCP银染技术对30例先天性巨结肠原癌基因RET第17外显子进行检测。
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