The tumor is associated with mutations of a protein called Rb, or retinoblastoma protein.
这种肿瘤与一种称作rb的蛋白，或视网膜母细胞瘤蛋白(retinoblastoma protein, prb)的突变有关。
Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle.
周期素d 1编码一种全酶的调节亚单位，该酶利用蛋白磷酸化灭活视网膜母细胞瘤蛋白，通过细胞周期G 1 - S期促进肿瘤进展恶化。
The active complex of cyclin D/CDK4 targets the retinoblastoma protein for phosphorylation, allowing the release of E2F transcription factors that activate G1/S-phase gene expression (3).
活跃的cyclinD/CDK4复合体靶向视网膜母细胞瘤蛋白以利于磷酸化，促进可以激活G1/S期基因表达的转录因子E2F的释放（3）。
The team's new research shows that miR-17 ~ 92 can also be involved in retinoblastoma, although it does not act in the same way, via the PTEN protein, as it does in other types of cancers.
这个团队的新研究显示，miR - 17 ~ 92还能够促进成视网膜细胞瘤的生长，不过这次并非通过PTEN蛋白发挥作用。
AIM: to investigate the expression of PTEN protein in retinoblastoma and its clinical significance.
目的：探讨pten蛋白在视网膜母细胞瘤组织中的表达及临床意义。
AIM: to investigate the expression of PTEN protein in retinoblastoma and its clinical significance.
目的：探讨pten蛋白在视网膜母细胞瘤组织中的表达及临床意义。
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