Objective To investigate whether the mutations in the cardiac sodium channel gene SCN 5 a can cause the idiopathic ventricular fibrillation (IVF).

目的研究心脏钠离子通道基因scn5A的突变是否能够引起自发性心室纤颤(ivf)，以帮助IVF的基因诊断和合理治疗。

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These included mutations in the sodium channel gene SCN5A, previously associated with LQTS and other unstable heart rhythm conditions and sudden death.

这其中包括钠通道基因scn5a的突变，该基因以前发现与LQTS、其他不稳定心律失常以及猝死相关。

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Conclusions the IVF with RBBB and st segment elevation is a distinct syndrome, and the mutations in the cardiac sodium channel gene SCN 5 a are associated with IVF.

结论我们的工作显示了伴有rbbb和ST段抬高的IVF是一种明显的综合征，并且心脏钠通道基因scn5A与IVF的发生密切相关。

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Methods PCR method was applied to detect the KDR mutation of the target site (sodium channel) gene.

方法采用聚合酶链反应(PCR)方法，用自行设计的特异引物，对昆虫的钠离子通道基因进行扩增。

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Methods PCR method was applied to detect the KDR mutation of the target site (sodium channel) gene.

方法采用聚合酶链反应(PCR)方法，用自行设计的特异引物，对昆虫的钠离子通道基因进行扩增。

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