Thirty percent of them were immunocompromised because of HIV infection, stem cell or solid organ transplantation, cancer, or high-dose steroid therapy.
其中30%是因为艾滋病毒感染,干细胞或实体器官移植,癌症,高剂量的类固醇治疗等免疫功能低下的人。
Immunologic disease can also complicate solid organ transplantation. Here is a renal biopsy that demonstrates marked interstitial fibrosis in a patient with chronic vascular rejection.
免疫疾病往往使实质脏器移植变得复杂。图示慢性血管排斥病人肾活检见间质纤维化。
Mycophenolate mofetil, the prodrug of the 2-(4morpholino) ethyl ester of mycophenolic acid, has been widely applied to the prophylaxis of acute graft rejection in solid organ transplantation.
麦考酚吗乙酯是麦考酚酸的2-乙基酯前体药物,临床广泛应用于器官移植后的抗排斥治疗。
IMPORTANCE OF THE FIELD: Invasive fungal diseases (IFD) are severe complications in patients receiving immunosuppression after solid organ or allogeneic stem cell transplantation.
研究领域的重要性:侵袭性真菌疾病(IFD)是实体器官或异基因干细胞移植术后接受免疫抑制治疗患者的严重并发症。
Immunosuppression in solid-organ recipients is associated with a greater risk of denovo malignancy after transplantation;
实体器官移植受者的免疫抑制与移植后的新发恶性肿瘤的危险有很大的相关性;
Immunosuppression in solid-organ recipients is associated with a greater risk of denovo malignancy after transplantation;
实体器官移植受者的免疫抑制与移植后的新发恶性肿瘤的危险有很大的相关性;
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