Objective To establish long-term cultured antigen-specific T cell line and clones and to analyze their T cell receptor usage.
目的体外建立可长期培养的抗原特异性T细胞系及克隆,并分析其T细胞受体的使用情况。
T cell receptor (TCR)gene rearrangement is an important event in T cell ontogeny that enables T cells to specifically recognise antigens, and any dysregulation in this process may result in diseases.
细胞在成熟过程中通过T细胞表面受体基因重排,从而具有特异性识别抗原的能力,在这一过程中的任何失调都会导致疾病。
In clinical practice we noticed that the successful implantation and the severity of GVHD were associated with t cell ratio of graft to receptor after pretreatment.
临床发现植入是否成功及GVHD的严重程度与预处理后供受体t细胞比例有关。
The positive rate of T-cell receptor gene rearrangement was 81.3%, and was independent of the histological features.
细胞受体基因重排的阳性率为81.3%,阳性率与疾病分期无关。
The magnitude and duration of T-cell immune response are critically regulated by the interaction of interleukin-2 (IL-2) and its high-affinity receptor (IL-2R) on the surface of the cell.
白细胞介素2 (IL - 2)与其高亲和力受体(IL - 2r)的相互作用在调节T细胞免疫反应的强度和持续时间方面起着关键作用。
Objective To investigate the type and the limitary shared of T-cell receptor(TCR) genes in tumor-infiltrating lymphocytes(TIL) of glioma specimens obtained.
目的 检测人脑胶质瘤中肿瘤浸润淋巴细胞 (TIL)是否存在抗原受体基因的限制性取用及其类型 ,探讨其免疫学和临床意义。
Although RU486 is progesterone antagonist in receptor level, no apoptotic cell death was found in the trophoblastic cells. According to referred data, only degeneration or necrosis t...
虽然RU486可在受体水平拮抗孕酮,但在滋养细胞及在脱膜细胞均无凋亡现象发生。
CCR5 protein coverage in the major T-cell surface, is a receptor protein.
CCR5蛋白质主要覆盖于T细胞表面,是一种蛋白受体。
"These structures, as well as other experiments we did, showed that the T-cell receptor USES a completely different recognition mechanism for the foreign and self MHC-protein complex," said Garcia.
Garcia说,这些结构,与我们在其他实验中做的同样好,表现出T细胞受体对异体和自体MHC -蛋白复合物使用完全不同识别机制。
Objective: to investigate the anti-tumor effects of murine T-lymphocytes harboring p185HER2 specific chimeric T-cell receptor gene.
目的:研究小鼠t淋巴细胞在转染嵌合性T细胞受体基因后的体外抗肿瘤作用。
Objective: to investigate the anti-tumor effects of murine T-lymphocytes harboring p185HER2 specific chimeric T-cell receptor gene.
目的:研究小鼠t淋巴细胞在转染嵌合性T细胞受体基因后的体外抗肿瘤作用。
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