The key to gene therapy is the selection of the target gene.
基因治疗的关键就是靶基因的选择。
We choose rotavirus SA11 strain VP4 gene as the target gene.
我们的研究选择了轮状病毒SA11株VP4基因作为目的基因。
The target gene couldn't express in NIH3T3 cells and blank control.
而转染鼠成纤维细胞NIH3T3，未见目的基因表达。
Objective To review the advances of target gene therapy of liver cancer.
目的介绍目前关于肝癌基因治疗靶向性研究的进展。
The regulation of a target gene expression is very important in gene therapy .
在基因治疗中，实现目的基因的调控表达是非常重要的。
Synthetic parameters of the PCR are very important to obtain ideal target gene.
获取理想的目的基因PCR反应的综合参数比十分重要。
Objective: to establish a stable cell line that can be induced to express a target gene.
目的：建立一个可诱导表达目的基因的细胞系以研究新基因的功能。
This study provides a basis for map-based cloning and functional analysis of the target gene.
本研究为该基因的图位克隆及功能解析奠定了基础。
The results of PCR demonstrated the integration of target gene into oil sunflower chromosome primarily.
PCR检测结果可初步证明目的基因的片段已转入到油葵细胞染色体中。
Conclusions Detection of target gene expression in paraffin-embedded tissues is feasible by RT-PCR or RQ-PCR.
结论应用RT-PCR或RQ-PCR方法在石蜡包埋组织中检测目的基因的表达是可行的。
Various chemical inducible systems based on activation and inactivation of the target gene had been described.
建立于目标基因激活和失活基础之上的几个化学分子诱导基因表达系统已有报道。
Objective To investigate the effects of target gene mutations on the quinolones resistance in Escherichia coli.
目的探讨大肠埃希菌靶位基因突变对喹诺酮类药物耐药的影响。
The VHL gene may be useful as a marker gene for the diagnosis of RCC and as a target gene for molecular therapy.
VHL基因可作为临床诊断指标，并可望成为肾透明细胞癌基因治疗的重要目的基因。
The invention also discloses a promoter used to guide the specific expression of target gene in insect hemocoel.
本发明还公开了一种可用于指导目的基因在昆虫血腔中特异表达的启动子。
To study the expression of PTEN, EGFR and P16 protein will build up target gene therapy foundation of astrocytoma.
通过对PTEN、EGFR、P 16蛋白的表达研究，为肿瘤的靶基因治疗策略提供了理论依据。
The expression of target gene being in said recombinant DNA in the new plant is controlled by proper chemical inducer.
在新的植物中该重组DNA中的目的基因的表达受合适的化学诱导物调控。
Mutations in the target gene appear as colorless plaques on a background of blue plaques when plated on indicator agar.
靶基因的变异表现为置于指示琼脂平板上的蓝色噬菌斑背景下的无色透明噬菌斑。
VEGF and its receptor-FLK - 1 may be the target gene of UPR, suggesting a mechanism of homeostasis of HBMEC under stress.
推测VEGF及其受体FLK一1可能为UPR的靶基因，这可能是人脑微血管内皮细胞在应激状态下保持自身稳定性的一种机制。
Both PR-A and PR-B are ligand activated, but differ in their relative ability to activate target gene transcription (3, 4).
PR A和PR B都是配体激活，但其激活靶基因转录的相对能力是不同的(3,4)。
If we can find a way to get to our target gene with a drug we may be able to help the millions of seniors with osteoporosis.
如果能够找到作用于靶基因的药物，就可以帮助数百万的骨质疏松老年患者。
The gene therapy is the target gene was modified with artificial methods, including gene transfer and gene being inactivated.
基因治疗是通过人工方法改变靶细胞的基因结构从而获得疗效，主要策略分为基因转移和基因灭活两大类。
Conclusion: the target gene and its fusion protein was successfully expressed, which provide a base for the further research.
结论：成功克隆葡糖基转移酶CAT基因并获得其融合蛋白的表达，为后续研究奠定了基础。
Conclusion GE7 system-mediated gene therapy system can transfer target gene to pituitary adenoma effectively and specifically.
结论GE7基因治疗系统能够达到靶向性治疗垂体腺瘤的目的。
There are many genetic transformation methods for the target gene getting into the receptor cell in plant genetic transformation.
在植物遗传化研究中，外源基因导入受体细胞的方法有多种。
It suggests that although -1892 and -1837 loci are far from the promoter, they may play a remote regulation on the target gene expression.
提示- 1892和- 1837两位点虽不在启动子区，但可能对靶基因表达具有一定的远端调控作用。
METHODS: We analyzed the gene sequences and protein structures of BMP-1 and its related proteins, and chose a highly conserved fragment as target gene.
方法：通过分析BMP - 1类各种分子的基因序列及蛋白结构，选择其中的一个片段作为目的基因。
The fact that 92.1% of lines were medium resistance or medium susceptible showed that target gene might only play partly role in sheath blight resistance.
但92.1％的株系表现为中抗或中感，表明转导目标基因可能仅起到部分提高抗性的作用。
The fact that 92.1% of lines were medium resistance or medium susceptible showed that target gene might only play partly role in sheath blight resistance.
但92.1％的株系表现为中抗或中感，表明转导目标基因可能仅起到部分提高抗性的作用。
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