Telomere and telomerase play important roles in the process of cellular senescence.
端粒及端粒酶在细胞的衰老过程中扮演着重要角色。
Telomere and telomerase is one of the updating issues highlighted in life science study.
端粒和端粒酶是近年来生命科学研究的热点问题之一。
The telomere and telomerase play an important role in the malignant progress of tumor cells and the maintenance of immortal cell lines.
端粒—端粒酶系统在肿瘤细胞的恶性进展和永生细胞的维护中起重要作用。
Following the importances of telomere and telomerase in senescence and tumor were recognized, the pathway of telomerase activation is becoming the focus of this area.
随着对端粒和端粒酶在衰老和肿瘤中重要性认识的不断深入，端粒酶的激活途径已日益成为这一研究领域的热点。
Telomere and telomerase are the focus of modern biological study. There are close relationships among telomere loss and cell ageing, activation of telomerase, cell senescence and immortalization.
端粒和端粒酶是现代生物学研究的热点，端粒的缺失与细胞的衰老，端粒酶的活性与细胞的老化及癌化均有密切的关系。
But if the telomerase enzyme is very active, telomere lengths are maintained and cells are kept young.
但是，如果端粒酶非常活跃的话，端粒的长度得以维持，而细胞则能保持年轻。
Conversely, if telomerase activity is high, telomere length is maintained, and cellular senescence is delayed. This is the case in cancer cells, which can be considered to have eternal life.
相反，如果端粒酶一直保持较高的活力，则端粒的长度就能保持下去，而细胞衰老的进程就会被推迟，这种情形可见于癌细胞：一类属于永生的细胞。
Objective: To study the changes of telomerase activity and telomere length.
目的：探讨肾癌组织端粒酶活性和端粒长度变化。
Telomerase is a kind of ERT which causes catalysis and prolong the end of telomere.
端粒酶，是一种催化延长端粒末端的反向转录酶。
Telomerase system is the genetic name of telomerase and telomere.
端粒酶系统是端粒和端粒酶的总称。
The main function of telomerase is for the replication of telomere DNA, which is closely related with tumor and cell senescence.
端粒酶的主要功能是复制端粒末端dna，维持端粒长度。端粒酶活性调节与肿瘤发生和细胞衰老有着密切关系。
Changes of telomere structure, length and expression of telomerase are regulated by a complex network of many associated proteins.
端粒的结构和长度变化、端粒酶的表达水平在众多相关蛋白所组成的复杂调控网络的作用下保持平衡。
Objectives: to establish a method of telomere repeat amplification protocol (TRAP) silver stain technique, and to investigate the significance of telomerase activity detection in tumor diagnosis.
目的：建立端粒重复序列扩增(TRAP)-银染色技术，探讨端粒酶活性检测在肿瘤诊断中的意义。
This article introduced telomere, telomerase, components of telomerase and their relation to cancer diagnosis.
本文介绍了端粒、端粒酶及其组分与肿瘤诊断的关系。
Telomerase and telomere-associated proteins can regulate telomere length.
端粒酶和端粒蛋白对端粒长度具有调节作用。
Objective To investigate changes of telomerase activities, and their affection on telomere length in irradiated human cell line A549.
目的观察人细胞系A549照射后端粒酶活性的变化及其对端粒长度的影响。
Telomere length and telomerase activity are important factors in the pathobiology of human disease.
端粒长度和端粒酶活性是人类疾病病理生物学中的重要因素。
Telomere, telomerase and its inhibitors are being extensively studied in the field of molecular and cellular biology and medicine.
端粒、端粒酶及其抑制剂研究是分子细胞生物学以及医学的热点之一。
Conclusion Telomere reduction and telomerase activation are critical factor during oncogenesis.
结论端粒缩短并激活端粒酶是涎腺肿瘤形成的重要因素。
Telomerase can extend the telomere of DNA and the activated telomerase can let cells gain the ability of unlimited reproduction.
端粒酶可延长染色体末端dna，端粒酶的活化使细胞获得无限增殖能力。
Another is the discovery of the enzyme telomerase, which keeps the telomere of our DNA healthy and operational, capable of giving human cells immortality.
另一个发现是控制端粒酶活性的酶。它们控制我们细胞的寿命。
It has been demonstrated that telomerase activity would be altered upon oxidative stress and excepted from nucleolus to mitochondria as well as telomere shortening.
现已发现，氧化应激可以改变端粒酶活性，促使端粒酶从细胞核转位到线粒体，因而不能继续维持端粒长度，使细胞端粒缩短。
Activation of telomerase can elongate telomere length and maintain gene stability.
端粒酶的活化可延长染色体的末端dna，维护基因组的稳定。
Activation of telomerase can elongate telomere length and maintain gene stability.
端粒酶的活化可延长染色体的末端dna，维护基因组的稳定。
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