We also established the cell line of this transgenic mice model through primary cell culture to make use this model more efficiently.
为了更为有效地利用该模型小鼠，我们通过原代培养建立了该模型的肿瘤细胞系。
In addition, transgenic mice performed normally in learning and memory in both place navigation training and the 1st spatial probe test.
在定位航行训练和第一次空间探索测试中，两组鼠在训练时逃避潜伏期及测试中在目标象限探索时间无统计学差异；
In other experiments, they discovered that "knocking" out the gene that produces SP in transgenic mice lowered their chances of acquiring the condition.
在其他的实验里，他们发现在转基因白鼠中，剔除那些制造“SP”物质的基因会降低他们得到那种疾病的概率。
Conclusion TRPV1 transgenic mice have been established successfully. The model will contribute to the further research of the physiological function of TRPV1.
结论成功建立了TRPV 1转基因小鼠模型，为深入研究TRPV1的功能提供了更好的条件。
Objective: to prepare a targeting drug for brain-derived neurotrophic factor (BDNF) and study its therapeutic effect in Alzheimer's disease (AD) transgenic mice.
目的：检测脑源性神经营养因子(BDNF)靶向药物对阿耳茨海默病(AD)转基因鼠的治疗作用。
The present invention also relates to a method of generation of fully functional heavy chain-only antibodies in transgenic mice in response to antigen challenge.
本发明还涉及在转基因小鼠中响应抗原激发产生全功能性仅有重链的抗体的方法。
As detected by Western blotting, TRPV1 expressions in the brain and skeletal muscle of the transgenic mice were significantly higher than the wild-type littermates.
经蛋白免疫印记法证实，与同窝野生型小鼠相比，转基因小鼠的脑组织和肌肉组织中TRPV1的表达显著升高。
Objective to construct heparin-binding epidermal growth factor-like growth factor transgenic mice in order to investigate the role of HB-EGF in the fibrosis of tissues.
目的建立系统表达肝素结合性表皮生长因子的转基因动物模型，利用转基因动物模型研究HB - EGF与组织纤维化的关系。
We also found positive transgenic mice in the kidney and spleen tissues of 5-LO, FLAP protein expression was significantly higher than normal mice by immunohistochemistry.
免疫组织化学等方法分析得到在转基因阳性鼠肾、脾组织中5-LO、FLAP蛋白的表达明显高于正常鼠。
Methods 3month old APP695 transgenic mice were randomly divided into model and Yizhi treatment groups, and negative transgenic mice were selected into normal control group.
方法APP695转基因小鼠分为AD模型组和益智汤治疗组，同月龄同背景转基因阴性小鼠为正常对照组。
Methods: APP transgenic mice of same age and APP positive control (divided in groups of difference by dosage) were selected to perform water maze and jump platform experiments.
方法：选用同龄转基因APP阳性动物(不同用药组)做水迷宫和跳台实验。
CONCLUSION: HNYCF evidently ameliorates the learning and memory ability in APP transgenic mice, which may be related to the anti-inflammatory and anti-oxidation effects of HNYCF.
结论：HNYCF可以改善APP转基因小鼠的学习记忆能力，其作用机制可能与抗炎、抗氧化作用有关。
The researchers tested transgenic mice that spontaneously develop IBD and then progress to colitis-associated colon cancer, producing the human version of MUC1 in both disease states.
研究者利用IBD自发转基因小鼠来进行试验，随后这些小鼠进展为肠炎相关性结肠癌，两种疾病均可产生异常增生的人类MUC1蛋白。
Objective To investigate the effect of dual-target antisense RNA of hepatitis B virus (HBV) targeted to X and P region on replication and expression of HBV gene in HBV transgenic mice.
目的探讨针对乙型肝炎病毒（HBV）x、p双靶区反义RNA对乙型肝炎病毒转基因小鼠HBV复制和表达的影响。
It is proved that the conformity site of exogenous gene in APP transgenic mice is random, the tumor induced by gene conformity site could manifest with different stage of cell growing.
结论证实了转基因动物导入外源性基因整合位点是随机的；整合位点引起的肿瘤可以随着细胞发育的不同阶段，逐渐的显现。
To analyze the antiviral efficacy, hepatitis B transgenic mice were treated either twice-weekly with AIC649 or twice daily with "gold standard" Tenofovir or vehicle over a period of 29 days.
为了分析AIC649抗病毒的疗效，研究人员给予转基因乙肝小鼠每周两次的 AIC649或“金标准”替诺福韦每日两次或用安慰剂治疗，疗程持续29天。
Therefore, we assessed adenosine levels and selective ar expression in transgenic mice with left ventricular systolic dysfunction secondary to overexpression of tumor necrosis factor - (TNF 1.6).
因此，我们检测了左心室收缩功能障碍并继发肿瘤坏死因子(TNF1.6)过表达的转基因老鼠腺苷水平和选择性ar的表达。
Objective: To explore the effect of transgenic metallothionein (MT) mushroom on anti-radiation ability of mice.
目的研究转金属硫蛋白基因平菇对小鼠抗辐射能力的影响。
Results The ultrastructure in the brain of mice in transgenic group had pathological changes compared with negative group.
结果与对照组比较，模型组小鼠海马神经细胞出现线粒体和突触损伤，血脑屏障结构异常。
Results The ultrastructure in the brain of mice in transgenic group had pathological changes compared with negative group.
结果与对照组比较，模型组小鼠海马神经细胞出现线粒体和突触损伤，血脑屏障结构异常。
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