Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.
一些小鼠还有肿瘤抑制基因p 53缺陷，这种缺陷突变存在与大约一半的人类肺癌。
They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.
他们发现当用DADS治疗时，有名的肿瘤抑制基因p53阻止了细胞循环 。
In 2005, researchers at Sloan-Kettering reported that the gene could stop massive tumor growth in prostate cancer even when another tumor suppressor, known as P53, was turned off.
早在2005年，斯隆·凯特琳中心的研究人员就曾报道了在另一种叫做P 53的肿瘤抑制基因关闭时，该基因甚至仍然可以阻止前列腺癌大肿瘤生长。
BRMS1 is a tumor metastasis suppressor gene discovered in breast carcinoma cells in 2000.
BRMS1是2000年在乳腺癌细胞中发现的癌转移抑制基因。
Tumor metastasis suppressor gene can inhibit the metastasis of tumor cells, mutations or deletions of this kind of genes can lead to tumor invasion and metastasis.
肿瘤转移抑制基因能抑制肿瘤细胞的转移，由于肿瘤转移抑制基因的突变或缺失，从而导致肿瘤的浸润和转移。
To investigate the suppression effect of tumor suppressor gene in lung adenocarcinoma cells.
探讨肿瘤抑制基因对肺腺癌细胞生长的抑制作用。
The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.
癌基因，肿瘤抑制基因的发现促进了对细胞周期及细胞凋亡机制的深入理解。使人们对肿瘤发生和发展的认识也日趋深入。
Heat Shock Proteins may contribute to cell cycle regulation by interacting with proto-oncogene products or tumor suppressor gene products.
热休克蛋白可能有助于细胞周期调控通过与原癌基因的产品或抑癌基因的产品。
It has been proved that the occurrence of oncogenesis is in close relationship with the oncogene activation, the tumor suppressor gene inactivation and the disorder of cell cycle modulation.
目前在分子水平上的研究显示肿瘤的发生与癌基因的激活和抑癌基因的失活以及细胞周期调节失控密切相关。
Recently researchers find that a new tumor suppressor imprinted gene ARHI(NOEY2)is involved in the onset and progression of cancer.
近年来研究表明，一种新的抑癌印迹基因ARHI（NOEY2）的异常参与了一些肿瘤的发生。
Quite a few kinds of genes such as susceptibility gene, oncogene and tumor suppressor genes have been found with implications for diagnosis, therapy and prognosis.
其中涉及多种基因异常，包括易感基因、癌基因、抑癌基因等，对于乳腺癌的诊断、治疗及预后判断均具有提示作用。
As a tumor-suppressor gene, phosphatase and tensin homology deleted on chromosome 10 (PTEN) regulates negatively the growth of tumor cells.
第10号染色体同源丢失性磷酸酶-张力蛋白基因(PTEN)作为肿瘤抑制基因，可以负性调节肿瘤细胞的生长。
A gene homologous to the human putative tumor suppressor gene QM, designated OSQM1, was isolated from rice Oryza sativa l.
基因组文库中分离到一个与人类肿瘤抑制基因QM具有同源性的基因，命名为OSQM1。
Conclusion Transfection of wild-type PTEN tumor suppressor gene might significantly reduce metastatic ability of human highly metastatic mucoepidermoid carcinoma cells.
结论转染野生型PTEN抑癌基因能降低人高转移性黏液表皮样癌细胞转移能力。
Objective To study effects of the exogenous wild-type PTEN tumor suppressor gene on in vitro adhesion, migration and invasion of the highly metastatic mucoepidermoid carcinoma cell line M3SP2.
目的探讨外源野生型PTEN抑癌基因对人高转移性黏液表皮样癌细胞系m 3sp2体外黏附、迁移和侵袭特性的影响。
They also raise the possibility that this important tumor-suppressor gene might play a role in miscarriages.
同样，这个重要的抑癌基因可能在流产中产生了重要的作用，它增加了流产发生的可能性。
There probably existed candidate tumor suppressor gene (s) around D5S592 and D5S471.
D5S471和D5S592附近可能存在食管癌的候选抑癌基因。
The different mechanisms, such as the activation of oncogenes, the inactivation and mutation of tumor suppressor gene, antiapoptosis and so on are involved in .
原癌基因的激活，抑癌基因的失活、突变，抗细胞凋亡等不同的机制都可能参与其中。
The UCSD researchers also studied mice that were missing a tumor suppressor gene, which is a gene that ACTS to prevent cell growth.
UCSD研究者也对丢失肿瘤抑制基因的小鼠进行研究。肿瘤抑制基因可以阻止细胞生长。
Objective To investigate the expression and significance of tumor suppressor gene protein PTEN in malignant melanoma.
目的探讨pten基因蛋白在恶性黑素瘤中的表达及其意义。
Objective To investigate the effect and mechanisms of tumor suppressor gene PTEN on the induction of anoikis of human bladder transitional carcinoma cells BIU-87.
目的研究抑癌基因pten对人膀胱癌细胞株biu - 87失巢凋亡的影响并探讨其可能的机制。
Objective: To explore the alteration and the possible mechanism of tumor suppressor gene P16 in the progression of ovarian carcinoma.
目的：探讨卵巢癌病变中P16抑癌基因的改变和可能的作用机制。
Tumor metastasis suppressor gene is a kind of genes that only suppresses metastasis without affecting tumorigenicity and tumor growth.
癌转移抑制基因是一类只抑制癌细胞的转移而不影响肿瘤的发生与生长的基因。
Objective to construct and express a recombinant adenovirus vector which can regulate expression of human tumor suppressor gene PTEN.
目的体外构建和表达可调控性人抑癌基因pten重组腺病毒。
Objective: To investigate the mutation of RB tumor suppressor gene in Wilms tumor and to explore the relationship between RB mutation and the pathogenesis of Wilms tumor.
目的：调查肾母细胞瘤中RB基因突变，探讨RB基因突变与肾母细胞瘤发生的关系。
Recently, the new discovered NM23 gene (a tumor metastasis suppressor gene) and PTEN gene (a tumor suppressor gene) cause people's attention extensively.
近来对新发现的肿瘤转移抑制基因NM 23和抑癌基因pten引起了人们极大关注。
The observations suggest that the tumor suppressor gene CDKN2 is a potential candidate for ge ne replacement therapy of NSCLC.
结果表明肿瘤抑制基因CDKN2可望成为NSCLC基因替代治疗的候选基因。
SIPA1 probably inhibits the metastasis and recurrence of HCC as a tumor suppressor gene.
SIPA1在HCC中发挥肿瘤抑制基因的作用，且对抑制HCC的复发转移有重要作用。
BRCA-1-associated protein (BAP1) is a tumor suppressor gene, which shows biallelic inactivation in approximately half of all mesotheliomas.
BRCA - 1相关蛋白(BAP1)是一种肿瘤抑制基因，约半数的间皮瘤中显示双等位基因失活。
BRCA-1-associated protein (BAP1) is a tumor suppressor gene, which shows biallelic inactivation in approximately half of all mesotheliomas.
BRCA - 1相关蛋白(BAP1)是一种肿瘤抑制基因，约半数的间皮瘤中显示双等位基因失活。
应用推荐