Aim: to investigate the relationship between the expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), cell proliferation and apoptosis in children's skin hemangioma.
目的探讨小儿皮肤血管瘤各阶段肿瘤坏死因子相关凋亡诱导配体(TRAIL)的表达与细胞增殖和凋亡的关系。
Objective: To explore the role of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL) combined with chemotherapeutic agents in treating neuroblastoma(NB) and the possible mechanism.
目的:探讨肿瘤坏死因子相关凋亡诱导配体(TRAIL)联合化疗药物治疗神经母细胞瘤(NB)的作用及其可能机制。
Objective to investigate the correlation between sensitivity to tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and expression level of death receptor 5 (DR5) on tumor cell surface.
目的探讨肿瘤细胞表面dr5表达水平与其对肿瘤坏死因子相关的凋亡诱导配体(TRAIL)敏感性之间的关系。
TNF related apoptosis inducing ligand (TRAIL) is a newly identified member of the tumor necrosis factor (TNF) family.
肿瘤坏死因子相关诱导凋亡配体(TRAIL)是TNF家族中的一个新型凋亡分子。
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
背景与目的:肿瘤坏死因子相关凋亡诱导配体(tumornecrosisfactor-relatedapoptosisinducingligand,TRAIL)有广谱的抗瘤作用,且对正常组织细胞无毒性,因此有望应用于肿瘤基因治疗。
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
背景与目的:肿瘤坏死因子相关凋亡诱导配体(tumornecrosisfactor-relatedapoptosisinducingligand,TRAIL)有广谱的抗瘤作用,且对正常组织细胞无毒性,因此有望应用于肿瘤基因治疗。
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