• Therefore, the aim of this study is to investigate the effects of genistein, a protein tyrosine kinase inhibitor, on acute and chronic inflammation in diabetic mice (induced by streptozotocin).

    因此研究目的调查金雀异黄素一种蛋白质酪氨酸激酶抑制剂对有急性慢性糖尿病炎症小鼠诱导脲佐菌素)的影响

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  • The drugs work by preventing an enzyme called tyrosine kinase from launching a signaling cascade that fuels tumor cell growth.

    这些药物作用机制是阻断酪氨酸激酶启动信号级联反应,后者可以促进肿瘤细胞生长

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  • CONCLUSION: CD117 can be regard as the related tumor antigen of MM, and may be a valuable marker in the use of tyrosine kinase selective inhibitors, which inhibit the signal conduct to the target.

    结论CD 117作为MM肿瘤相关抗原作为靶向信号转导抑制剂酪氨酸激酶选择性抑制剂应用有价值标志

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  • Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.

    非替尼为选择性EGFR一蛋白酪氨酸激酶抑制剂阻断酪氨酸蛋白激酶信号传导通路从而促进肿瘤细胞凋亡。

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  • Growth factor and tyrosine kinase mediated signaling is activated and the signaling against cell proliferation is inhibited in some extent, which show a state of system complexity.

    生长因子酪氨酸激酶介导信号传导有不同程度激活,而增殖和免疫防御的信号传导受到不同程度的抑制表现出一种系统复杂性的状态

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  • Sunitinb is a novel multitargeted receptor tyrosine kinase inhibitor.

    苏尼替尼新型的多靶点酪氨酸激酶抑制剂

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  • Objective: to establish a method of detecting insulin receptor tyrosine kinase (IRTK) activity from erythrocytes.

    目的建立红细胞胰岛素受体酪氨酸蛋白激酶(IRTK)的活性测定

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  • CONCLUSIONS AG1109 not only was an effective inhibitor of protein tyrosine kinases, but also was a novel potent inhibitor of protein kinase CK2.

    结论AG110 9不仅酪氨酸蛋白激酶抑制剂而且一种十分有效的蛋白激酶CK2的抑制剂。

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  • Genistein, a natural tyrosine kinase inhibitor, has been reported to inhibit growth and induce apoptosis of various Turner cells.

    金雀异黄素一种天然酪氨酸激酶抑制剂可以抑制多种肿瘤细胞的增殖,诱发细胞凋亡

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  • JAK2 is a constitutive protein tyrosine kinase (PTK) which can activate JAK-STAT signaling.

    JAK2一种组成性酪氨酸激酶激活JAK - STAT信号传导途径

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  • Ibrutinib (ibr), a first-in-class, once-daily, oral, covalent inhibitor of Bruton's tyrosine kinase (BTK), is rapidly eliminated from plasma after oral administration (Advani, JCO 2013).

    鲁替尼——首创药物,每天口服一次,布鲁酪氨酸激酶BTK共价抑制剂——口服给药之后快速细胞内清除。

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  • The tyrosine phosphorylated 130000 protein was identified as JAK2, a non receptor tyrosine kinase.

    鉴定了分子量为130000酪氨酸磷酸化蛋白质JAK2一种受体型酪氨酸激酶

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  • The tyrosine phosphorylated 130000 protein was identified as JAK2, a non receptor tyrosine kinase.

    鉴定了分子量为130000酪氨酸磷酸化蛋白质JAK2一种受体型酪氨酸激酶

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