Therefore, the aim of this study is to investigate the effects of genistein, a protein tyrosine kinase inhibitor, on acute and chronic inflammation in diabetic mice (induced by streptozotocin).
因此,本研究的目的是调查金雀异黄素,一种蛋白质酪氨酸激酶抑制剂,对有急性或慢性糖尿病炎症小鼠(诱导脲佐菌素)的影响。
The drugs work by preventing an enzyme called tyrosine kinase from launching a signaling cascade that fuels tumor cell growth.
这些药物的作用机制是阻断酪氨酸激酶启动信号级联反应,后者可以促进肿瘤细胞生长。
CONCLUSION: CD117 can be regard as the related tumor antigen of MM, and may be a valuable marker in the use of tyrosine kinase selective inhibitors, which inhibit the signal conduct to the target.
结论CD 117可作为MM的肿瘤相关抗原,也可作为靶向信号转导抑制剂酪氨酸激酶选择性抑制剂应用的有价值的标志。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂,能阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡。
Growth factor and tyrosine kinase mediated signaling is activated and the signaling against cell proliferation is inhibited in some extent, which show a state of system complexity.
生长因子与酪氨酸激酶介导的信号传导有不同程度的激活,而抗增殖和免疫防御的信号传导受到不同程度的抑制,表现出一种系统复杂性的状态。
Sunitinb is a novel multitargeted receptor tyrosine kinase inhibitor.
苏尼替尼是一种新型的多靶点酪氨酸激酶抑制剂。
Objective: to establish a method of detecting insulin receptor tyrosine kinase (IRTK) activity from erythrocytes.
目的:建立红细胞胰岛素受体酪氨酸蛋白激酶(IRTK)的活性测定法。
CONCLUSIONS AG1109 not only was an effective inhibitor of protein tyrosine kinases, but also was a novel potent inhibitor of protein kinase CK2.
结论:AG110 9不仅是酪氨酸蛋白激酶的抑制剂,而且是一种十分有效的蛋白激酶CK2的抑制剂。
Genistein, a natural tyrosine kinase inhibitor, has been reported to inhibit growth and induce apoptosis of various Turner cells.
金雀异黄素是一种天然的酪氨酸激酶抑制剂,可以抑制多种肿瘤细胞的增殖,并诱发细胞凋亡。
JAK2 is a constitutive protein tyrosine kinase (PTK) which can activate JAK-STAT signaling.
JAK2是一种组成性酪氨酸激酶,能激活JAK - STAT信号传导途径。
Ibrutinib (ibr), a first-in-class, once-daily, oral, covalent inhibitor of Bruton's tyrosine kinase (BTK), is rapidly eliminated from plasma after oral administration (Advani, JCO 2013).
依鲁替尼——首创药物,每天口服一次,布鲁顿酪氨酸激酶(BTK)的共价抑制剂——口服给药之后可快速从浆细胞内清除。
The tyrosine phosphorylated 130000 protein was identified as JAK2, a non receptor tyrosine kinase.
鉴定了分子量为130000酪氨酸磷酸化的蛋白质为JAK2,一种非受体型酪氨酸激酶。
The tyrosine phosphorylated 130000 protein was identified as JAK2, a non receptor tyrosine kinase.
鉴定了分子量为130000酪氨酸磷酸化的蛋白质为JAK2,一种非受体型酪氨酸激酶。
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