Colon cancer could express VEGF-C, and influence lymphatic metastasis in colon cancer.
结肠癌可表达VEGF - C,并影响结肠癌的淋巴转移。
MVD and VEGF-C are probably the dangerous factors in patients who had blood metastasis.
MVD及VEGF - C可能是乳腺癌患者发生血行转移的危险因素。
The expression of MVD and VEGF-C in breast cancer was closely related to blood metastasis.
MVD及VEGF-C的阳性表达与乳腺癌血行转移危险密切相关。
Background and objective It has been showed that VEGF-C can induce the proliferation of lymphocytes.
背景与目的血管内皮生长因子c (VEGF - C)可以诱导淋巴管上皮细胞增殖和淋巴窦的新生。
VEGF-C and its receptor VEGFR-2/VEGFR-3 are the key players in the molecular regulation of lymphangiogenesis.
VEGF-C主要通过其受体VEGFR-2、VEGFR-3发挥作用,是一种重要的血管、淋巴管内皮细胞调节因子。
The expression of VEGF-C was correlated with portal vein-emboli, lymph node metastasis and recurrence(P<0.05).
癌组织中VEGF -C的表达与门静脉癌栓、肝门淋巴结转移和复发有关(P<0.05)。
To discuss the relationships between VEGF-C expression, lymphatic metastasis and clinical pathologic characteristics.
探讨结肠癌组织中血管内皮生长因子- C (VEGF - C)表达与淋巴转移、临床病理参数之间的关系。
Results There was no expression of VEGF-C in normal colorectal tissues, but VEGFR-3 expressed in the lymphatic endothelium.
结果正常大肠组织内未见VEGF - C阳性表达,但可见淋巴管内皮细胞VEGFR - 3阳性表达。
It is significant to research the relationship between COX-2 and VEGF-C in lymph node metastasis mechanism of breast cancer.
因此,在乳腺癌中,研究COX - 2和vegf - C之间的关系对明确乳腺癌淋巴结转移发病机制具有重要意义。
The relationship between the VEGF-C expression in malignant tumor tissues and lymphatic metastasis is still scarcely reported.
目前恶性肿瘤组织中vegf—c的表达与肿瘤淋巴转移的关系方面的研究资料尚少。
Objective to investigate the effects of vascular endothelial growth factor-C (VEGF-C) on lymphangiogenesis in adenocarcinoma of rectum.
目的探讨血管内皮生长因子c在直肠腺癌淋巴管生成中的作用。
VEGF-C in human ovarian promoted tumor cell proliferation, invasion and metastasis, was related to epithelial ovarian cancer prognosis.
VEGF - C诱导卵巢肿瘤细胞的增殖,促进侵袭及转移,与上皮性卵巢肿瘤的预后有关。
Conclusion The expressions of VEGFR-3 and VEGF-C in breast cancer have close relations with lymph node metastasis and clinical TNM stages.
结论VEGFR - 3和vegf - C在乳腺癌中的表达与肿瘤临床分期及淋巴结转移的关系密切。
Conclusion VEGF-C may be related to invasion, lymph node metastasis and postoperative hematogenous metastasis of the carcinoma and prognosis.
结论VEGF - C与食管鳞癌的侵袭、淋巴结转移、手术后血性转移以及预后有一定关系。
Objective To discuss the relationship between VEGF-C expression and lymphatic metastasis on patients with diabetes mellitus and colon cancer.
目的探讨结肠癌合并糖尿病患者血管内皮生长因子-C(VEGF-C)表达情况与淋巴转移的关系。
Objective:To explore the different expression of IGF-IR and VEGF-C in Esophageal Squamous Cell Carcinoma(ESCC) and the adjacent normal tissue.
目的:探讨食管鳞癌组织及癌旁正常组织中胰岛素样生长因子-I受体(IGF-IR)、血管内皮生长因子C因子(VEGF-C)的表达及其意义。
VEGF-C and VEGF-D are of clinical significance in evaluating lymph node metastatic potency and estimation of prognosis in gallbladder carcinoma.
VEGF - C和VEGF - D在评价胆囊癌淋巴转移潜力和评估预后具有重要的临床意义。
VEGF-C/ VEGFR-3 (FLT-4) signalling which is mediated of lymphogenesis or dilation of lymphatics is closely correlated with lymphogenesis of tumor.
信号系统是淋巴管生成或扩张的信号通路,与肿瘤淋巴管的生成密切相关。
Conlusion The expression of VEGF-C are correlated with difference type of thyroid cancer and its prognosis. VEGF-C is related to lymph node metastasis.
结论VEGF - C表达与甲状腺癌病理分型及预后可能有一定关系,与甲状腺癌淋巴结转移密切相关。
Objective: To investigate the expression of VEGF-C in colorectal cancer and evaluate the relationship between VEGF-C expression and lymph node metastasis.
前言:目的:探讨血管内皮生长因子c (VEGF C)在人结直肠癌中的表达及与肿瘤淋巴结转移之间的关系。
Conclusion: the peri-tumoral lymphatic vessels are associated with lymph node metastasis and VEGF-C may related to the generation of lymphatic vessels in OSCC.
结论:口腔鳞癌肿瘤边缘区淋巴管与淋巴结转移相关,VEGF - C可能参与口腔鳞癌淋巴管的形成。
BACKGROUND: There are many researches indicating that vascular endothelial growth factor-C (VEGF-C) is closely associated with lymph node metastasis of malignant tumor.
学术背景:不少研究表明血管内皮生长因子c与恶性肿瘤的淋巴道转移密切相关。
Vascular endothelial growth factors such as VEGF-C and VEGF-D can induce the growth of tumor lymphatic vessels and promote tumor metastasis through the lymphatic system.
血管内皮生长因子- C (VEGF - C)和血管内皮生长因子d (VEGF - D)可以诱导肿瘤新生淋巴管形成,并促进肿瘤淋巴道转移。
Methods Specimens were obtained from 30 patients with rectum adenocarcinoma, and examined for the expression of VEGF-C and VEGFR-3 in carcinoma region and normal region.
方法取人直肠腺癌手术材料30例,用免疫组化方法检测癌区和癌周正常区vegf - C和VEGFR - 3的表达情况。
The positive expression rates of VEGFR-3 and VEGF-C in breast cancer with lymph node metastasis were significantly higher than that without lymph node metastasis(P<0.05);
乳腺癌组织中VEGFR-3和VEGF-C阳性表达率在有、无淋巴结转移组之间的差异均有显著性(P<0.05);
The aim of this article is to investigate the effects on lymphangiogenesis of orthotopic implantation of lung cancer in nude mice with antisense oligonucleotides of VEGF-C.
本研究目的旨在观察脂质体介导的VEGF - C反义寡核苷酸对肺癌裸鼠皮下种植瘤模型微淋巴管生成的影响。
Conclusion: VEGF-C is expressed in part of the rectal cancer cases, and its expressions were closely correlated with lymphatic metastasis, and the degree of lymphatic metastasis.
结论:VEGF - C表达于部分直肠癌中,其表达与直肠癌淋巴结转移显著相关,并且与直肠癌淋巴结转移程度显著相关。
Conclusion: There is no obvious lymphatic hyperplasia and up-regulation of VEGF-C in acute inflammatory tissue. The opening lumen is just a change caused by functional adaptation.
结论:急性炎症不仅没有明显的淋巴管增生,而且也没有明显的VEGF - C表达增高,管腔增大仅是适应功能的改变。
Conclusion the overexpression of VEGF-C and VEGFR-3 in rectum adenocarcinoma may promote the hyperplasia and dilation of lymphatics, and the lymphatic metastasis of the cancer cells.
结论VEGF - C和VEGFR - 3在人直肠腺癌中的过表达,可能与淋巴管增生和扩张,促进癌细胞的淋巴转移有关。
Conclusion the overexpression of VEGF-C and VEGFR-3 in rectum adenocarcinoma may promote the hyperplasia and dilation of lymphatics, and the lymphatic metastasis of the cancer cells.
结论VEGF - C和VEGFR - 3在人直肠腺癌中的过表达,可能与淋巴管增生和扩张,促进癌细胞的淋巴转移有关。
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