Because these genes are carried on the X-chromosome, they are subject to a process known as X-chromosome inactivation.
由于这些基因存在于X染色体上,它们发生了X染色体失活的处理。
This phenomenon is mostly seen in imprinted genes and X-chromosome inactivation where DNA methylation of promoter regions leads to repression of gene expression.
这种现象主要在印迹基因和X染色体失活区域看到,这些区域中的启动子区的DNA甲基化导致了基因表达的抑制。
To assess the clonal origin of renal clear cell carcinomas by the study of X-chromosome inactivation pattern in female clear cell renal carcinomas and normal renal tissues.
本实验将通过研究女性肾透明细胞癌及正常肾组织的X染色体失活类型判断肾透明细胞癌克隆起源。
X inactivation starts at the X inactivation center (XIC) and spreads throughout the chromosome.
失活开始于XIC,然后传播到整条染色体。
Objective To explore the relationship between X - linked spondyloepiphyseal dysplasia tarda (SEDL) gene escaping X chromosome inactivation( XCI) and SEDL phenotype.
目的探讨X-连锁迟发性脊椎骨骺发育不良(SEDL)基因逃避X染色体失活(XCI)及与临床表型的关系。
Objective to study the clonality of palmar fibromatosis by molecular genetic analysis of X chromosome inactivation pattern at a polymorphic site of human androgen receptor gene (HUMARA).
目的通过人雄激素受体(HUMARA)基因位点克隆性分析技术确定掌纤维瘤病是否为肿瘤性增生。
Objective to study the clonality of palmar fibromatosis by molecular genetic analysis of X chromosome inactivation pattern at a polymorphic site of human androgen receptor gene (HUMARA).
目的通过人雄激素受体(HUMARA)基因位点克隆性分析技术确定掌纤维瘤病是否为肿瘤性增生。
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