目的探讨不孕不育及自发流产与染色体核型异常的关系，指导临床对这些疾病的诊断。
Objective: To investigate the relationship between sterility, spontaneous abortion and abnormal chromosome karyotypes, and that would be help for clinical diagnose for hereditary disease.
结果：发现164例染色体异常核型，占全部受检病例的15.53%。
Results: 164 cases of chromosomal abnormal karyotype accounted for 15.53%.
父母的行为与其胎儿染色体核型正常或异常关系不大。
Parents' behaviour had little correlation with fetus chromosome abnormalities.
结论在染色体异常核型中，均有不同程度的基因缺失，造成基因连锁的不平衡，因而出现一些临床效应。
Conclusion: gene have different degree loses in abnormal chromosome karyogram, result in chromosomal gene linkage not equilibrium and and emergence clinical effect.
结论染色体异常是闭经的主要原因之一，染色体核型分析对闭经患者的诊断和治疗是必要的。
Conclusion: chromosome abnormality is one of the main causes of amenorrhea. Karyotype analysis of chromosome is absolutely necessary for the diagnosis and treatment of patient with amenorrhea.
结果：146例外周血染色体异常核型中常染色体数目异常占4.8％（7/146）； 常染色体结构异常占29.5％（43/146）；
Results: In 146 cases of chromosomes aberrance, the rate of abnormal eu-chromosome number and abnormal euchromosome structure was 4. 8% (7/146) and 29. 5% (43/146).
方法采用低叶酸tc 199培养诱导法，观察了31对染色体核型无异常的习惯性流产夫妇染色体脆性位点，并观察了脆性位点的分布。
Methods: TC199 low level of folic acid cultivation method was performed to analyse both the frequency and the distribution of chromosome fragile sites in 31 habitual abortion couples.
本文并对优生咨询者染色体异常核型与不同类型表型两者的相关性进行了探讨，这对优生咨询具有指导意义。
The chromosomal abnormalities of birth health counselee relationship between karyotype and phenotype of different kinds were discussed. There are guide significance for birth health counseling.
目的了解男性染色体异常核型对优生优育的影响。
Methods Abnormal karyotype of chromosome in 123 males were undergone cytogenetic analysis.
结果由于染色体核型异常的不同，出现不同的临床效应。
Results: Observation 26 Cases with different degree abnormal chromosome karyogram have different degree clinical effect.
本研究将染色体多态核型人群和正常核型人群分组，进行G显带染色体核型分析，以比较两组人群的生殖异常的发生率。
The incidence rates of reproduction abnormality of chromosome polymorphism group and normal karyotype group have been compared by G-banded chromosome karyotype analysis.
结果对照组性染色体核型均正常，难免流产组性染色体核型异常2例，但两组的差异无显著性；
Results Nuclear types of normal villous tissues were all normal. There were 2 cases with abnormal nuclear types in inevitable abortion group, but the difference was not significant.
结果128例胎儿核型中，9例为18三体综合征，2例为其它染色体异常，染色体异常发现率为8·59%（11/128）。
Results Nine cases of trisomy 18 and 2 cases of other abnormal karyotype were found among the 128 pregnant women (8.59%, 11/128).
方法：对近6年于北京大学人民医院不孕不育门诊进行咨询的1624例患者中，存在染色体异常的患者，进行染色体核型及临床分析。
Methods: Among 1624 patients consulted in infertility clinic in our hospital from recent 6 years, chromosome karyotype and clinical analysis were conducted in abnormal chromosome patients.
染色体多态性17例，占异常核型的9.83%，主要包括Y染色体多态性、次缢痕和随体的变异。
There were 17 cases of chromosome polymorphism, accounting for 9.83% of all abnormal karyotypes. It contains Y chromosome, secondary constriction, and variation of satellites.
结果分析2 35对自然流产夫妇的染色体核型，发现异常37例，异常发生率为7 87%。
Results There were 37 abnormal karyotypes in 235 couples with spontaneous abortions. The rate of abnormal karyotypes was 7.87%.
结果显示永生化胚胎肝细胞克隆形成率为31.2%，染色体核型分析表明细胞核型无明显异常，软琼脂集落形成试验表明细胞在软琼脂中不能生长。
It is showed that the cell clone-forming rat was 31. 2%. The immortalized human fetal hepatocytes had a normal karyotype and were not able to grow in soft AGAR culture.
克氏症仍是最常见的染色体疾病，染色体平衡易位核型占常染色体异常核型比例最大。
Klinefelter syndrome is still the most common chromosomal disease, balanced translocation accounts for largest proportion of autosomal abnormality.
克氏症仍是最常见的染色体疾病，染色体平衡易位核型占常染色体异常核型比例最大。
Klinefelter syndrome is still the most common chromosomal disease, balanced translocation accounts for largest proportion of autosomal abnormality.
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