本文主要概述了微生物来源的醛糖还原酶抑制剂的研究进展。
This review mainly gives a brief account of the progress of research on aldose reductase inhibitors from microorganisms.
在试管内，未磷酸化的醛糖还原酶和磷酸化的醛糖还原酶的动力学常数无差异，而细胞内的情况有待于进一步研究。
The phosphorylation assay proves that aldose reductase is the substrate of insulin-receptor tyrosine kinase and the Tyr(40) and Tyr(49) are phosphorylated by the kinase.
中药制剂的实验药理研究主要集中在抗氧化作用、抑制醛糖还原酶作用和抑制晶状体上皮细胞凋亡方面。
Pharmacological experiments of Chinese herbal medicine were focused on antioxidant effect and inhibiting aldose reductase and decreasing apoptosis of lens epithelial cell.
醛式糖还原酶是通常是存在在眼睛和在许多其它身体部位的酵素。
Aldose reductase is an enzyme that is normally present in the eye and in many other parts of the body.
醛糖还原酶是多元醇代谢通路中的限速酶，醛糖还原酶抑制剂能有效抑制此通路，减慢或改善糖尿病并发症。
Aldose reductase is a key rate?limiting enzyme in the pathway, while aldose reductase inhibitors can inhibit the pathway and alleviate the symptoms of diabetic complications.
目的探讨醛糖还原酶相似基因- 1 (ARL - 1基因)与人肝癌细胞耐药性的关系。
Objective To investigate the relationship between aldose reductase-like-1 (ARL-1) gene and drug resistance in human liver carcinoma cells.
醛糖还原酶(AR)在糖性白内障和其它糖尿病并发症的发病中起着关键性的作用。
Aldose reductase (ar) plays an important role in sugar cataract and other complications of diabetes.
目的找出优化NADP生成荧光法测定红细胞醛糖还原酶(AR)活性的方案。
Objective To optimize the the NADPgenerating fluorimetric method for aldose reductase (AR) activity.
观察了一种醛糖还原酶抑制剂（ICI 128436）对小鼠胰岛体外培养时山梨醇代谢的影响情况。
The effect of ICI 128436, an aldose reductase inhibitor on the sorbitol metabolism in the mouse pancreatic islets during in vitro culture was observed.
人们正在研究防止或减缓(阻断)醛式糖还原酶的药物，用以防止或延迟糖尿病综合症动。
Drugs that prevent or slow (inhibit) the action of aldose reductase are being studied as a way to prevent or delay these complications of diabetes.
因此，醛糖还原酶抑制剂成为公认的预防、改善和治疗糖尿病并发症的有效对策。
Therefore, ALR2 inhibition has received attention as an attractive strategy to prevent or delay the onset and to minimize the seriousness of chronic diabetic complications.
因此，醛糖还原酶抑制剂成为公认的预防、改善和治疗糖尿病并发症的有效对策。
Therefore, ALR2 inhibition has received attention as an attractive strategy to prevent or delay the onset and to minimize the seriousness of chronic diabetic complications.
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