目的:考察环丙沙星聚乳酸微球的体外释药性能。
Objective: To study the release of ciprofloxacin polylactic acid microspheres in vitro.
采用不同的表面活性剂制备得到不同表面电荷性质的聚乳酸微球。
Poly (lactic acid) microspheres with different surface charges have been prepared by using cationic, anionic or nonionic surfactants as the microspheres' surface stabilizers.
结论布洛芬聚乳酸微球在一定浓度下可以作为一种局部缓释药物应用于颅内。
Conclusion: The ibuprofen polylactide microspheres could be used as a local slow release drug in cranial under a certain concentration.
目的:对阿霉素聚乳酸微球的制备工艺、含量测定及体外释药特性进行初步研究。
OBJECTIVE To study the preparation process, assay and in vitro drug release of adriamycin polylactic acid microspheres.
目的考察聚乳酸相对分子量对利福平聚乳酸微球形态、载药量及微球中药物分布状态的影响。
Aim To discover the effect of molecular weight of polylactic acid on the shape, drug content and drug distribution state of rifampicin polylactic acid microspheres.
方法:测定破伤风类毒素聚乳酸微球免疫动物后1年中动物血清抗体反应及疫苗制剂的生物利用度。
Methods: The antibody levels elicited by microsphere formulations in mice for 1 year were examined, and the bioavailability of microsphere formulations was calculated.
方法以聚乳酸为载体材料,OW型乳化挥发法制备氟尿嘧啶微球;
METHODS An O/W emulsion-solvent evaporation method was used to prepare fluorouracil sustained release microspheres.
在此基础上,采用乳化溶剂挥发法和液致相分离相结合制备了聚乳酸多孔微球。
Moreover, PLA porous microspheres were fabricated by solution induced phase separation based on emulsion-solvent evaporation.
结论:聚乳酸大蒜素微球具有良好的缓释作用。
Conclusion: Diallyl trisulfide microspheres have obviously sustained effect.
以聚乳酸为载体材料制备阿奇霉素微球(AZMMS)并考察其体外释药特性。
To prepare microsphere containing Azithromycin(AZM) with polylactic acid, and investigate the characteristics of AZM microsphere (AZMMS)in vitro release.
本文主要综述了明胶、壳聚糖、聚乳酸这三种常用的可生物降解的载药微球的研究进展。
Latest research progress of microspheres containing drugs used three commonly biodegradable materials which were gelatin, chitosan and polylactide was summarized.
本文主要综述了明胶、壳聚糖、聚乳酸这三种常用的可生物降解的载药微球的研究进展。
Latest research progress of microspheres containing drugs used three commonly biodegradable materials which were gelatin, chitosan and polylactide was summarized.
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